Synthroid and Neosporin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Neosporin (neomycin sulfate; polymyxin b sulfate). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Neosporin. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

What is Neosporin?

Neosporin has active ingredients of neomycin sulfate; polymyxin b sulfate. eHealthMe is studying from 954 Neosporin users. Check the latest studies of Neosporin.

On Jul, 17, 2026

27 people who take Synthroid and Neosporin together, and have interactions are studied.

Synthroid and Neosporin drug interactions.

What are the common drug interactions of Synthroid and Neosporin, by gender? *:

female:

Pain
Dyspnoea (difficult or laboured respiration)
Decreased interest
Dehydration (dryness resulting from the removal of water)
Dental caries
Diarrhoea
Electrolyte imbalance
Gastritis (inflammation of stomach)
General physical health deterioration (weak health status)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

male:

n/a

What are the common drug interactions of Synthroid and Neosporin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Fibromyalgia (a long-term condition which causes pain all over the body)

50-59:

Dyspnoea (difficult or laboured respiration)
Face oedema (swelling of face)
Fibromyalgia (a long-term condition which causes pain all over the body)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gallbladder disorder
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hospitalisation
Ill-defined disorder
Oxygen saturation decreased
Pain

60+:

Pain
Abdominal pain
Dental caries
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Electrolyte imbalance
Gastritis (inflammation of stomach)
General physical health deterioration (weak health status)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 33.33%
High Blood Pressure: 3 people, 11.11%
Skin Wrinkling (wrinkle on skin): 2 people, 7.41%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.41%
Pain: 2 people, 7.41%
Hyperthyroidism (over activity of the thyroid gland): 2 people, 7.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.41%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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