Tagamet and Mefenamic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tagamet (cimetidine) and Mefenamic acid (mefenamic acid). Common drug interactions include nausea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tagamet and Mefenamic acid. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.

What is Mefenamic acid?

Mefenamic acid has active ingredients of mefenamic acid. It is often used in painful menstrual periods. eHealthMe is studying from 4,844 Mefenamic acid users. Check the latest studies of Mefenamic acid.

On Jul, 21, 2026

16 people who take Tagamet and Mefenamic acid together, and have interactions are studied.

Tagamet and Mefenamic acid drug interactions.

What are the common drug interactions of Tagamet and Mefenamic Acid, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Vomiting
Hepatocellular damage (liver damage)
Pruritus (severe itching of the skin)
Urine discolouration
Abdominal pain upper
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arthralgia (joint pain)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)

male:

Chronic kidney disease
Depression
Dyspepsia (indigestion)
Headache (pain in head)
Insomnia (sleeplessness)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Renal failure (kidney dysfunction)

What are the common drug interactions of Tagamet and Mefenamic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hepatic function abnormal
Thrombocytopenia (decrease of platelets in blood)
Hepatocellular damage (liver damage)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Urine discolouration
Vomiting

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)

50-59:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Depression
Dyspepsia (indigestion)
Headache (pain in head)
Insomnia (sleeplessness)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Memory impairment
Rash erythematous (redness of the skin)
Rash pruritic (redness with itching)

60+:

n/a

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 31.25%
Pain: 3 people, 18.75%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 12.50%
Inflammation: 2 people, 12.50%
Infection: 2 people, 12.50%
Headache (pain in head): 2 people, 12.50%
The Flu (the flu is caused by an influenza virus): 2 people, 12.50%
High Blood Cholesterol: 2 people, 12.50%
Gingival Disorder (gum disease): 1 person, 6.25%
Gastric Ulcer (stomach ulcer): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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