Tapazole and Dexamethasone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tapazole (methimazole) and Dexamethasone (dexamethasone). Common drug interactions include headache among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Tapazole and Dexamethasone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Tapazole?
Tapazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 2,477 Tapazole users. Check the latest studies of Tapazole.
What is Dexamethasone?
Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.
17 people who take Tapazole and Dexamethasone together, and have interactions are studied.

What are the common drug interactions of Tapazole and Dexamethasone, by gender? *:
female:
- Headache (pain in head)
- Pain
- Abdominal pain
- Amylase increased
- Blood cholinesterase decreased
- Blood creatinine increased
- Enteritis (inflammation of the small intestine)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Vomiting
male:
- Death
- Neoplasm malignant (cancer tumour)
What are the common drug interactions of Tapazole and Dexamethasone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Anxiety
- Asthenia (weakness)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Cough
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Hyperkalaemia (damage to or disease of the kidney)
- Hypernatraemia (an abnormally high plasma concentration of sodium ions)
60+:
- Asthenia (weakness)
- Decreased appetite
- Blood creatinine increased
- Enteritis (inflammation of the small intestine)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Vomiting
- White blood cell count decreased
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
What are the existing conditions these people have? *
- Breast Cancer Metastatic: 6 people, 35.29%
- Gastric Cancer (stomach cancer): 3 people, 17.65%
- Breast Cancer: 2 people, 11.76%
- High Blood Cholesterol: 2 people, 11.76%
- Thyroid Neoplasm (tumour of thyroid): 1 person, 5.88%
- Thyroid Diseases: 1 person, 5.88%
- Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 1 person, 5.88%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.88%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.88%
- Depression: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Tapazole and Dexamethasone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Tapazole (2,477 reports)
- Dexamethasone (161,927 reports)
Browse all drug interactions of Tapazole and Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tapazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tapazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexamethasone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on methimazole and dexamethasone (the active ingredients of Tapazole and Dexamethasone, respectively), and Tapazole and Dexamethasone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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