Tapazole and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tapazole (methimazole) and Seroquel (quetiapine fumarate). Common drug interactions include pneumonia among females and hypomania among males.

The phase IV clinical study analyzes what interactions people have when they take Tapazole and Seroquel. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Tapazole?

Tapazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 2,477 Tapazole users. Check the latest studies of Tapazole.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

On Aug, 09, 2026

47 people who take Tapazole and Seroquel together, and have interactions are studied.

Tapazole and Seroquel drug interactions.

What are the common drug interactions of Tapazole and Seroquel, by gender? *:

female:

Pneumonia
Rash
Renal failure (kidney dysfunction)
Renal hypertension (high blood pressure caused by the kidneys hormonal response)
Renal injury (kidney injury)
Somnolence (a state of near-sleep, a strong desire for sleep)
Upper respiratory tract infection
Vertigo
Abdominal pain upper
Anxiety

male:

Hypomania (a mild form of mania, marked by elation and hyperactivity)
Platelet count decreased
Malaise (a feeling of general discomfort or uneasiness)
Weight increased
Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
Neurasthaenia (a psychological disorder characterized by chronic fatigue and weakness, loss of memory, and generalized aches and pains)
Photosensitivity reaction
Skin exfoliation (removal of the oldest dead skin cells)
Sleep disorder
Weakness

What are the common drug interactions of Tapazole and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cholecystitis acute (rapid infection of gallbladder)
Nephrolithiasis (calculi in the kidneys)
Suicidal ideation
Gallbladder disorder
Gallbladder enlargement
Weight increased

30-39:

Anxiety
Cardiac disorder
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Drug ineffective
Fatigue (feeling of tiredness)
Intentional self-injury
Menstruation irregular
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain
Suicide attempt

40-49:

Diabetes mellitus inadequate control
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hyperglycaemia (high blood sugar)
Tardive dyskinesia (a disorder that involves involuntary movements)
Type 1 diabetes mellitus
Type 2 diabetes mellitus
Adverse drug reaction
Agitation (state of anxiety or nervous excitement)
Drug effect decreased
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

50-59:

Abdominal pain upper
Constipation
Diarrhoea
Vomiting
C-reactive protein increased
Pancreatitis (inflammation of pancreas)
Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
Skin exfoliation (removal of the oldest dead skin cells)
Anxiety
Blood cholesterol increased

60+:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Sopor (sleep)
Fall
Fatigue (feeling of tiredness)
Upper respiratory tract infection
Subgaleal haematoma (bleeding in the potential space between the skull periosteum and the scalp galea aponeurosis)
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Hepatotoxicity (chemical-driven liver damage)
Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 18 people, 38.30%
Sleep Disorder: 9 people, 19.15%
Stress And Anxiety: 5 people, 10.64%
Depression: 5 people, 10.64%
Parkinson's Disease: 3 people, 6.38%
Pain: 3 people, 6.38%
Nausea And Vomiting: 3 people, 6.38%
Nausea (feeling of having an urge to vomit): 3 people, 6.38%
High Blood Pressure: 3 people, 6.38%
Headache (pain in head): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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