Tarka and Fosamax drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tarka (trandolapril; verapamil hydrochloride) and Fosamax (alendronate sodium). Common drug interactions include oral herpes among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Tarka and Fosamax. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Tarka?
Tarka has active ingredients of trandolapril; verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,409 Tarka users. Check the latest studies of Tarka.
What is Fosamax?
Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,452 Fosamax users. Check the latest studies of Fosamax.
25 people who take Tarka and Fosamax together, and have interactions are studied.

What are the common drug interactions of Tarka and Fosamax, by gender? *:
female:
- Oral herpes (viral infection of mouth)
- Oral torus (a lesion made of compact bone and occurs along the palate or the mandible inside the mouth)
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
- Sinusitis (inflammation of sinus)
- Small cell lung cancer stage unspecified (lung cancer in unknown stage)
- Upper respiratory tract infection
- Vocal cord paralysis
- Ankle fracture
- Cardiac failure congestive
- Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
male:
- Fall
- Intervertebral disc degeneration (spinal disc degeneration)
- Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
- Depression
- Emotional distress
- Fatigue (feeling of tiredness)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Fibula fracture
- Foot fracture
- Joint injury
What are the common drug interactions of Tarka and Fosamax, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Anxiety
- Road traffic accident
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
- Sinusitis (inflammation of sinus)
- Small cell lung cancer stage unspecified (lung cancer in unknown stage)
- Upper respiratory tract infection
- Vocal cord paralysis
- Ankle fracture
- Fall
- Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
What are the existing conditions these people have? *
- Blood Pressure Abnormal: 5 people, 20.00%
- Pain: 4 people, 16.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.00%
- Migraine (headache): 3 people, 12.00%
- High Blood Cholesterol: 3 people, 12.00%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 12.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 12.00%
- Stress And Anxiety: 2 people, 8.00%
- Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 8.00%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Tarka and Fosamax?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tarka and Fosamax:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tarka:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fosamax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tarka and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fosamax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on trandolapril; verapamil hydrochloride and alendronate sodium (the active ingredients of Tarka and Fosamax, respectively), and Tarka and Fosamax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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