Tazorac and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tazorac (tazarotene) and Simvastatin (simvastatin). Common drug interactions include cholestasis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tazorac and Simvastatin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Tazorac?

Tazorac has active ingredients of tazarotene. It is often used in acne. eHealthMe is studying from 1,046 Tazorac users. Check the latest studies of Tazorac.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

On Jul, 26, 2026

13 people who take Tazorac and Simvastatin together, and have interactions are studied.

Tazorac and Simvastatin drug interactions.

What are the common drug interactions of Tazorac and Simvastatin, by gender? *:

female:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Back pain
Blood alkaline phosphatase increased
Diarrhoea
Drug ineffective
Eating disorder
Feeling cold

male:

Chronic kidney disease
Allergy to plants
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal tubular necrosis (death of kidney tubules)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Drug ineffective
Influenza
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Pneumonia

What are the common drug interactions of Tazorac and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal tubular necrosis (death of kidney tubules)

50-59:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Back pain
Diarrhoea
Drug ineffective
Eating disorder
Feeling cold
Headache (pain in head)
Hot flush (sudden feelings of heat)
Micturition urgency (urgency to pass the urine)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

Allergy to plants
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Viral infection
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Hepatocellular damage (liver damage)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Influenza

What are the existing conditions these people have? *

Irritable Bowel Syndrome: 3 people, 23.08%
Muscle Spasms (muscle contraction): 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Cardiac Disorder: 3 people, 23.08%
Blood Pressure Abnormal: 3 people, 23.08%
Infection: 3 people, 23.08%
Inflammation: 3 people, 23.08%
Migraine (headache): 3 people, 23.08%
Diabetes: 3 people, 23.08%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 23.08%

* Approximation only. Some reports may have incomplete information.

Do you take Tazorac and Simvastatin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously