Tekturna and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tekturna (aliskiren hemifumarate) and Acetaminophen (acetaminophen). Common drug interactions include gastrointestinal disorder among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Tekturna and Acetaminophen. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.



On Jul, 11, 2026

33 people who take Tekturna and Acetaminophen together, and have interactions are studied.

Tekturna and Acetaminophen drug interactions.

What are the common drug interactions of Tekturna and Acetaminophen, by gender? *:

female:

  1. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  2. Glomerular filtration rate decreased
  3. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
  4. Hyperglycaemia (high blood sugar)
  5. Influenza
  6. Injection site mass
  7. Insomnia (sleeplessness)
  8. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  9. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  10. Malaise (a feeling of general discomfort or uneasiness)

male:

  1. Back pain
  2. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  3. Arthralgia (joint pain)
  4. Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
  5. Asthma
  6. Atelectasis (partial or complete collapse of the lung)
  7. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  8. Conjunctival haemorrhage (bleeding underneath the conjunctiva)
  9. Conjunctivitis (pink eye)
  10. Cough

What are the common drug interactions of Tekturna and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood creatinine increased
  2. Chronic kidney disease
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Hair colour changes

50-59:

  1. Renal tubular necrosis (death of kidney tubules)
  2. Secondary hyperthyroidism
  3. Chronic kidney disease
  4. Renal failure (kidney dysfunction)
  5. Depression
  6. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Post-traumatic stress disorder
  9. Renal injury (kidney injury)

60+:

  1. Back pain
  2. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  3. Anaemia (lack of blood)
  4. Anxiety
  5. Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  9. Blood albumin decreased
  10. Blood creatinine increased

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 24.24%
  2. High Blood Cholesterol: 8 people, 24.24%
  3. Muscle Spasms (muscle contraction): 5 people, 15.15%
  4. Constipation: 5 people, 15.15%
  5. Thrombocytopenia (decrease of platelets in blood): 4 people, 12.12%
  6. Asthma: 4 people, 12.12%
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 12.12%
  8. Septic Shock (shock due to blood infection): 4 people, 12.12%
  9. Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 12.12%
  10. Infection: 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

Do you take Tekturna and Acetaminophen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tekturna and Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tekturna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tekturna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on aliskiren hemifumarate and acetaminophen (the active ingredients of Tekturna and Acetaminophen, respectively), and Tekturna and Acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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