Tekturna and Isosorbide mononitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tekturna (aliskiren hemifumarate) and Isosorbide mononitrate (isosorbide mononitrate). Common drug interactions include pain among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tekturna and Isosorbide mononitrate. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

On Aug, 02, 2026

27 people who take Tekturna and Isosorbide mononitrate together, and have interactions are studied.

Tekturna and Isosorbide mononitrate drug interactions.

What are the common drug interactions of Tekturna and Isosorbide Mononitrate, by gender? *:

female:

Pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pain in extremity
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Burning sensation
Chronic kidney disease
Drug dependence
Dry mouth
Lacrimation increased

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Local swelling (swelling at the site of some application of substance or injury)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Renal failure acute (rapid kidney dysfunction)
Renal impairment (severely reduced kidney function)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Weight increased
Cardiac disorder
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Tekturna and Isosorbide Mononitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cardiac disorder
Dyspepsia (indigestion)

50-59:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Burning sensation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug dependence
Dry mouth
Lacrimation increased
Limb discomfort (discomfort in leg)
Low density lipoprotein increased (cholesterol increased in blood)
Muscle rigidity (muscle stiffness)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dizziness
Fall
Femur fracture
Fracture displacement
Haematuria (presence of blood in urine)
Haemorrhage (bleeding)
Hypervolaemia (abnormally increased volume of blood)
Limb discomfort (discomfort in leg)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 48.15%
Pain: 10 people, 37.04%
Diabetes: 8 people, 29.63%
High Blood Cholesterol: 7 people, 25.93%
Infection: 7 people, 25.93%
Depression: 7 people, 25.93%
Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 22.22%
Gastric Ulcer (stomach ulcer): 5 people, 18.52%
Chest Pain: 5 people, 18.52%
Cardiac Disorder: 5 people, 18.52%

* Approximation only. Some reports may have incomplete information.

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