Tekturna and Wellbutrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tekturna (aliskiren hemifumarate) and Wellbutrin (bupropion hydrochloride). Common drug interactions include nightmare among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Tekturna and Wellbutrin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,110 Wellbutrin users. Check the latest studies of Wellbutrin.



On Aug, 07, 2026

37 people who take Tekturna and Wellbutrin together, and have interactions are studied.

Tekturna and Wellbutrin drug interactions.

What are the common drug interactions of Tekturna and Wellbutrin, by gender? *:

female:

  1. Nightmare (unpleasant dream)
  2. Restless legs syndrome (a powerful urge to move your legs)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Urinary retention (the inability to completely or partially empty the bladder)
  5. Urinary tract infection
  6. Weight decreased
  7. Alopecia (absence of hair from areas of the body)
  8. Aortic valve sclerosis (narrowing of the aortic valve)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Bladder outlet obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded)

male:

  1. Abdominal pain
  2. Dyspepsia (indigestion)
  3. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  4. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  5. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  6. Urinary tract infection
  7. Vision blurred
  8. Agitation (state of anxiety or nervous excitement)
  9. Aggression
  10. Confusional state

What are the common drug interactions of Tekturna and Wellbutrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal pain
  2. Bradycardia (abnormally slow heart action)
  3. Cerebral infarction (less blood supply to brain resulting tissue damage)
  4. Dyspepsia (indigestion)
  5. Encephalopathy (functioning of the brain is affected by some agent or condition)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Hyperglycaemia (high blood sugar)
  8. Hyperlipidaemia (presence of excess lipids in the blood)
  9. Leukocytosis (increased white blood cells)
  10. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)

30-39:

  1. Drug ineffective
  2. Muscle spasms (muscle contraction)
  3. Rash macular (small, flat red spots)

40-49:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)

50-59:

  1. Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
  2. Hepatic steatosis (fatty liver disease)
  3. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  4. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  5. Hypercholesterolaemia (high levels of cholesterol in the blood)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))
  8. Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood)
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  10. Hypovolaemia (a decreased volume of circulating blood in the body)

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Nervousness
  3. Heart rate decreased
  4. Muscle spasms (muscle contraction)
  5. Nausea (feeling of having an urge to vomit)
  6. Nightmare (unpleasant dream)
  7. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  8. Pain
  9. Palpitations (feelings or sensations that your heart is pounding or racing)
  10. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 8 people, 21.62%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.22%
  3. Pain: 6 people, 16.22%
  4. Asthma: 6 people, 16.22%
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 5 people, 13.51%
  6. Insomnia (sleeplessness): 5 people, 13.51%
  7. High Blood Cholesterol: 5 people, 13.51%
  8. Neuropathy Peripheral (surface nerve damage): 5 people, 13.51%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 13.51%
  10. Diarrhea: 4 people, 10.81%

* Approximation only. Some reports may have incomplete information.

Do you take Tekturna and Wellbutrin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tekturna and Wellbutrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tekturna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Wellbutrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tekturna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Wellbutrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on aliskiren hemifumarate and bupropion hydrochloride (the active ingredients of Tekturna and Wellbutrin, respectively), and Tekturna and Wellbutrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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