Temozolomide and Gemcitabine hydrochloride drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Temozolomide (temozolomide) and Gemcitabine hydrochloride (gemcitabine hydrochloride). Common drug interactions include ascites among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Temozolomide and Gemcitabine hydrochloride. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Temozolomide?
Temozolomide has active ingredients of temozolomide. It is often used in glioblastoma multiforme. eHealthMe is studying from 16,644 Temozolomide users. Check the latest studies of Temozolomide.
What is Gemcitabine hydrochloride?
Gemcitabine hydrochloride has active ingredients of gemcitabine hydrochloride. eHealthMe is studying from 14,775 Gemcitabine hydrochloride users. Check the latest studies of Gemcitabine hydrochloride.
25 people who take Temozolomide and Gemcitabine hydrochloride together, and have interactions are studied.

What are the common drug interactions of Temozolomide and Gemcitabine Hydrochloride, by gender? *:
female:
- Ascites (accumulation of fluid in the abdominal cavity)
- Neoplasm progression (growth of tumour)
- Malignant neoplasm progression (cancer tumour came back)
- Desmoplastic small round cell tumour (soft tissue cancer)
- Metastases to lymph nodes (cancer spreads to lymph node)
- Metastases to liver (cancer spreads to liver)
- Metastases to peritoneum (cancer spreads to peritoneum)
- Breast cancer metastatic
- Metastases to lung (cancer spreads to lung)
- Disease progression
male:
- Drug ineffective
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
- Biliary sepsis
- Desmoplastic small round cell tumour (soft tissue cancer)
- Disease recurrence
- Febrile neutropenia (fever with reduced white blood cells)
- Haematotoxicity (toxins that destroy red blood cells)
- Neoplasm progression (growth of tumour)
- Prostatitis (inflammation of the prostate gland)
What are the common drug interactions of Temozolomide and Gemcitabine Hydrochloride, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Ascites (accumulation of fluid in the abdominal cavity)
- Neoplasm progression (growth of tumour)
- Malignant neoplasm progression (cancer tumour came back)
- Desmoplastic small round cell tumour (soft tissue cancer)
- Metastases to lymph nodes (cancer spreads to lymph node)
- Metastases to liver (cancer spreads to liver)
- Metastases to peritoneum (cancer spreads to peritoneum)
- Disease progression
- Bone marrow failure
- Drug ineffective
20-29:
n/a
30-39:
- Haematotoxicity (toxins that destroy red blood cells)
- Neoplasm progression (growth of tumour)
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
- Biliary sepsis
- Desmoplastic small round cell tumour (soft tissue cancer)
- Disease recurrence
- Drug ineffective
- Febrile neutropenia (fever with reduced white blood cells)
40-49:
- Renal failure (kidney dysfunction)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
50-59:
n/a
60+:
- Neutropenia (an abnormally low number of neutrophils)
- Prostatitis (inflammation of the prostate gland)
- Thrombocytopenia (decrease of platelets in blood)
What are the existing conditions these people have? *
- Desmoplastic Small Round Cell Tumor: 20 people, 80.00%
- Malignant Neoplasm Progression (cancer tumour came back): 3 people, 12.00%
* Approximation only. Some reports may have incomplete information.
Do you take Temozolomide and Gemcitabine hydrochloride?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Temozolomide (16,644 reports)
- Gemcitabine hydrochloride (14,775 reports)
Browse all drug interactions of Temozolomide and Gemcitabine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Temozolomide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gemcitabine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Temozolomide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gemcitabine hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on temozolomide and gemcitabine hydrochloride (the active ingredients of Temozolomide and Gemcitabine hydrochloride, respectively), and Temozolomide and Gemcitabine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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