Terazosin hydrochloride and Benadryl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Terazosin hydrochloride (terazosin hydrochloride) and Benadryl (diphenhydramine hydrochloride). Common drug interactions include osteonecrosis of jaw among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Terazosin hydrochloride and Benadryl. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Terazosin hydrochloride?

Terazosin hydrochloride has active ingredients of terazosin hydrochloride. It is often used in prostate examination abnormal. eHealthMe is studying from 2,352 Terazosin hydrochloride users. Check the latest studies of Terazosin hydrochloride.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,955 Benadryl users. Check the latest studies of Benadryl.

On Aug, 09, 2026

16 people who take Terazosin hydrochloride and Benadryl together, and have interactions are studied.

Terazosin hydrochloride and Benadryl drug interactions.

What are the common drug interactions of Terazosin Hydrochloride and Benadryl, by gender? *:

female:

Osteonecrosis of jaw (death of bone of jaw)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
Pain
Pleural fibrosis (formation of fibrous tissue in lung)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pulmonary air leakage
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pyrexia (fever)
Rash

male:

Anxiety
Arthropod sting (arthropod bite)
Blood bilirubin increased
Blood creatinine increased
Blood pressure decreased
Blood urea increased
Blood uric acid increased
Bone density decreased
Circulatory collapse
Death

What are the common drug interactions of Terazosin Hydrochloride and Benadryl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Pyrexia (fever)
Rash
Rectal polyp (fleshy growth occurring on the lining of the colon)
Renal failure acute (rapid kidney dysfunction)
Retching (strong involuntary effort to vomit)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Right ventricular hypertrophy (right ventricular enlargement)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Sinusitis (inflammation of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Arthropod sting (arthropod bite)
Blood glucose increased
Blood urea increased
Blood uric acid increased
Circulatory collapse
Dizziness
Eye haemorrhage (bleeding in the eye)
Heart rate irregular
Intervertebral disc protrusion (spinal disc protrusion)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 25.00%
Itching: 3 people, 18.75%
Pain: 2 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
Vasculitis (inflammation of a blood vessel or blood vessels): 1 person, 6.25%
Heart Rate Irregular: 1 person, 6.25%
Appetite Disorder (abnormal eating habits): 1 person, 6.25%
Bone Density Abnormal: 1 person, 6.25%
Bone Disorder: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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