Testosterone and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Testosterone (testosterone) and Codeine (codeine sulfate). Common drug interactions include localised infection among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Testosterone and Codeine. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Testosterone?

Testosterone has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 6,457 Testosterone users. Check the latest studies of Testosterone.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

On Aug, 05, 2026

54 people who take Testosterone and Codeine together, and have interactions are studied.

Testosterone and Codeine drug interactions.

What are the common drug interactions of Testosterone and Codeine, by gender? *:

female:

Localised infection (infection at the single location)
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Nasopharyngitis (inflammation of the nasopharynx)
Oral herpes (viral infection of mouth)
Peripheral coldness
Pleurisy (inflammation of the pleurae, which causes pain when breathing)

male:

Drug ineffective
Device dislocation
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Acidosis (build-up of carbon dioxide in the blood)
Drug resistance (reduction in effectiveness of a drug)
Hyperkalaemia (damage to or disease of the kidney)
Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)
Hypotension (abnormally low blood pressure)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Migraine (headache)

What are the common drug interactions of Testosterone and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Ventricular extrasystoles (premature cardiac contraction)
Drug abuse
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Muscle rigidity (muscle stiffness)
Acidosis (build-up of carbon dioxide in the blood)
Hyperkalaemia (damage to or disease of the kidney)
Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)

30-39:

Priapism (prolonged and painful erection that can last from several hours up to a few days)
Venous occlusion (the blocking of venous return)
Drug ineffective
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Infusion related reaction
Panic attack
Throat irritation

40-49:

Polyp
Acute myocardial infarction (acute heart attack)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Colon cancer
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

50-59:

Device dislocation
Drug ineffective
Abdominal distension
Diarrhoea

60+:

Cough
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Migraine (headache)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Prostate infection
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Cyst (a closed sac)
Dermal cyst
Hypersensitivity

What are the existing conditions these people have? *

Prinzmetal Angina (cardiac chest pain at rest that occurs in cycles): 12 people, 22.22%
Osteoporosis (bones weak and more likely to break): 10 people, 18.52%
Migraine (headache): 10 people, 18.52%
Headache (pain in head): 10 people, 18.52%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 16.67%
Hypotension (abnormally low blood pressure): 9 people, 16.67%
Cough: 9 people, 16.67%
Diarrhea: 9 people, 16.67%
Dyspnea (difficult or laboured breathing): 9 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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