Theo-dur and Revatio drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Theo-dur (theophylline) and Revatio (sildenafil citrate). Common drug interactions include pneumonia bacterial among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Theo-dur and Revatio. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Theo-dur?
Theo-dur has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 4,451 Theo-dur users. Check the latest studies of Theo-dur.
What is Revatio?
Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.
11 people who take Theo-dur and Revatio together, and have interactions are studied.

What are the common drug interactions of Theo-Dur and Revatio, by gender? *:
female:
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Anaphylactic reaction (serious allergic reaction)
- Drug hypersensitivity
- Hypersensitivity
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Abdominal distension
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
- Catheter site pain
- Catheter site swelling
male:
- Dyspnoea (difficult or laboured respiration)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Oedema peripheral (superficial swelling)
- Hypoxia (low oxygen in tissues)
- Insomnia (sleeplessness)
- Platelet count decreased
- Pneumonia
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Abdominal pain upper
- Disease progression
What are the common drug interactions of Theo-Dur and Revatio, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Abdominal distension
- Anaphylactic reaction (serious allergic reaction)
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
- Catheter site pain
- Catheter site swelling
- Diarrhoea
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
60+:
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Dyspnoea (difficult or laboured respiration)
- Abdominal pain upper
- Disease progression
- Dizziness
- Lung disorder (lung disease)
- Oedema peripheral (superficial swelling)
- Hypoxia (low oxygen in tissues)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Insomnia (sleeplessness)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 81.82%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 36.36%
- Dermatitis Allergic (inflammation of the skin due allergic reaction): 4 people, 36.36%
- Constipation: 4 people, 36.36%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 36.36%
- Cardiac Failure: 4 people, 36.36%
- Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 4 people, 36.36%
- Pneumonia: 3 people, 27.27%
- Hypokalemia (low potassium): 3 people, 27.27%
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 3 people, 27.27%
* Approximation only. Some reports may have incomplete information.
Do you take Theo-dur and Revatio?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Theo-dur and Revatio:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Theo-dur:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Revatio:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Theo-dur and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revatio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on theophylline and sildenafil citrate (the active ingredients of Theo-dur and Revatio, respectively), and Theo-dur and Revatio (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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