Tikosyn and Cipro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tikosyn (dofetilide) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include cognitive disorder among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Tikosyn and Cipro. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

19 people who take Tikosyn and Cipro together, and have interactions are studied.

What are the common drug interactions of Tikosyn and Cipro, by gender? *:

female:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dizziness
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Back pain
Cerebral haemorrhage (bleeding within the brain)
Colon spastic (stiffness of colon)
Diabetic ulcer
Dizziness (excl vertigo)
Drug ineffective
Dyspepsia (indigestion)

male:

Fatigue (feeling of tiredness)
Abdominal pain
Neck pain
Pain
Partner stress
Syncope (loss of consciousness with an inability to maintain postural tone)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Renal cell carcinoma (a kidney cancer)

What are the common drug interactions of Tikosyn and Cipro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cerebral haemorrhage (bleeding within the brain)
Colon spastic (stiffness of colon)
Diabetic ulcer
Dyspepsia (indigestion)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastric irritation (stomach irritation)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Head injury
Infected skin ulcer

60+:

Fatigue (feeling of tiredness)
Abdominal pain
Neck pain
Pain
Partner stress
Syncope (loss of consciousness with an inability to maintain postural tone)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Renal cell carcinoma (a kidney cancer)

What are the existing conditions these people have? *

Atrial Tachycardia (rhythm disturbance that arises in the atria): 4 people, 21.05%
Salmonella Enterocolitis (an infection in the lining of the small intestine caused by salmonella bacteria): 1 person, 5.26%
Lung Injury: 1 person, 5.26%
Arrhythmias (irregular heartbeat): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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