Timolol and Zetia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Timolol (timolol) and Zetia (ezetimibe). Common drug interactions include migraine with aura among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Timolol and Zetia. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Timolol?

Timolol has active ingredients of timolol. It is often used in glaucoma. eHealthMe is studying from 9,142 Timolol users. Check the latest studies of Timolol.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

53 people who take Timolol and Zetia together, and have interactions are studied.

What are the common drug interactions of Timolol and Zetia, by gender? *:

female:

Migraine with aura (headache with vision weakness)
Mobility decreased (ability to move is reduced)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Nervousness

male:

Chronic kidney disease
Death
Ageusia (loss of taste functions of the tongue)
Ammonia increased
Anosmia (partial or complete loss of the sense of smell)
Anxiety
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Confusional state

What are the common drug interactions of Timolol and Zetia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anxiety
Depression
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)

50-59:

Back pain
Low density lipoprotein increased (cholesterol increased in blood)
Nerve injury
Pain
Pain in extremity
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Heart valve incompetence (heart's valves do not work correctly)
Type 2 diabetes mellitus

60+:

Chronic kidney disease
Diarrhoea
Adverse event
Ageusia (loss of taste functions of the tongue)
Ammonia increased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anosmia (partial or complete loss of the sense of smell)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Balance disorder

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 11 people, 20.75%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 10 people, 18.87%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 16.98%
Pain: 7 people, 13.21%
High Blood Pressure: 7 people, 13.21%
Type 2 Diabetes: 6 people, 11.32%
Stress And Anxiety: 6 people, 11.32%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 9.43%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.66%
Headache (pain in head): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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