Tizanidine hydrochloride and Cannabis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tizanidine hydrochloride (tizanidine hydrochloride) and Cannabis (marijuana). Common drug interactions include hallucination among females and multiple sclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Tizanidine hydrochloride and Cannabis. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Tizanidine hydrochloride?

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 7,453 Tizanidine hydrochloride users. Check the latest studies of Tizanidine hydrochloride.

What is Cannabis?

Cannabis has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 13,371 Cannabis users. Check the latest studies of Cannabis.

On Jul, 17, 2026

17 people who take Tizanidine hydrochloride and Cannabis together, and have interactions are studied.

Tizanidine hydrochloride and Cannabis drug interactions.

What are the common drug interactions of Tizanidine Hydrochloride and Cannabis, by gender? *:

female:

Hallucination (an experience involving the perception of something not present)
Visual impairment
Constipation
Ocular hyperaemia (an abnormally large amount of blood in eye)
Abdominal discomfort
Chronic kidney disease
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Drug ineffective
Migraine (headache)
Alopecia (absence of hair from areas of the body)

male:

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Aggression
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Chills (felling of cold)
Constipation
Cough
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Depression
Diplopia (double vision)

What are the common drug interactions of Tizanidine Hydrochloride and Cannabis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alopecia (absence of hair from areas of the body)
Somnolence (a state of near-sleep, a strong desire for sleep)
Surgery
Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
Weight decreased
Abortion spontaneous (naturally occurring miscarriage)
Aggression
Agitation (state of anxiety or nervous excitement)
Impatience (restlessness)
Pregnancy

40-49:

Abdominal discomfort
Chronic kidney disease
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Abdominal pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Cough
Dizziness

50-59:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Chills (felling of cold)
Constipation
Cough
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Depression
Diplopia (double vision)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)

60+:

Constipation
Hallucination (an experience involving the perception of something not present)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Visual impairment
Drug ineffective

What are the existing conditions these people have? *

Pain: 4 people, 23.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 23.53%
Dyskinesia (abnormality or impairment of voluntary movement): 3 people, 17.65%
Abdominal Discomfort: 2 people, 11.76%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 11.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.76%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 11.76%
Depression: 2 people, 11.76%
Affective Disorder (mental disorder): 1 person, 5.88%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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