Topamax and Lactase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Lactase (lactase). Common drug interactions include chest discomfort among females and sinusitis among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Lactase. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,955 Topamax users. Check the latest studies of Topamax.

What is Lactase?

Lactase has active ingredients of lactase. It is often used in lactose intolerance. eHealthMe is studying from 948 Lactase users. Check the latest studies of Lactase.



On Aug, 02, 2026

11 people who take Topamax and Lactase together, and have interactions are studied.

Topamax and Lactase drug interactions.

What are the common drug interactions of Topamax and Lactase, by gender? *:

female:

  1. Chest discomfort
  2. Chest pain
  3. Chronic kidney disease
  4. Diarrhoea
  5. Drug ineffective
  6. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  7. Heart valve incompetence (heart's valves do not work correctly)
  8. Hernia obstructive (obstruction in the bowel; interrupt the blood supply to the herniated tissue)
  9. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  10. Implant site pain

male:

  1. Sinusitis (inflammation of sinus)
  2. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  3. Chronic kidney disease
  4. Hospitalisation
  5. Opiates positive
  6. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  7. Urine amphetamine positive
  8. Vomiting

What are the common drug interactions of Topamax and Lactase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Heart valve incompetence (heart's valves do not work correctly)
  2. Implant site pain
  3. Implant site vesicles
  4. Mitral valve incompetence (inefficient heart valve)
  5. Pulmonary arterial pressure increased
  6. Right atrial dilatation (enlargement of the right atrium chamber of heart)
  7. Tricuspid valve incompetence (inefficient heart valve)

30-39:

  1. Chronic kidney disease
  2. Drug ineffective
  3. Infection
  4. Injection site cyst
  5. Injection site rash
  6. Skin lesion
  7. Staphylococcal infection (an infection with staphylococcus bacteria)

40-49:

  1. Chest discomfort
  2. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  3. Infusion related reaction

50-59:

  1. Abdominal pain
  2. Back pain
  3. Nausea (feeling of having an urge to vomit)
  4. Neck pain
  5. Pain in extremity
  6. Sinus disorder (disease of sinus)
  7. Chest pain
  8. Diarrhoea
  9. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  10. Hernia obstructive (obstruction in the bowel; interrupt the blood supply to the herniated tissue)

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 36.36%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 27.27%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 9.09%
  4. Suicidal Ideation: 1 person, 9.09%
  5. Skin Wrinkling (wrinkle on skin): 1 person, 9.09%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 9.09%
  7. Prolactinoma (benign tumour (adenoma) of the pituitary gland that produces a hormone called prolactin): 1 person, 9.09%
  8. Pituitary Tumor Benign: 1 person, 9.09%
  9. Pain: 1 person, 9.09%
  10. Osteoporosis (bones weak and more likely to break): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Topamax and Lactase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lactase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topamax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lactase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on topiramate and lactase (the active ingredients of Topamax and Lactase, respectively), and Topamax and Lactase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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