Topicort and Lipitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topicort (desoximetasone) and Lipitor (atorvastatin calcium). Common drug interactions include application site vesicles among females and gastrooesophageal reflux disease among males.

The phase IV clinical study analyzes what interactions people have when they take Topicort and Lipitor. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Topicort?

Topicort has active ingredients of desoximetasone. eHealthMe is studying from 3,423 Topicort users. Check the latest studies of Topicort.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.



On Jul, 13, 2026

29 people who take Topicort and Lipitor together, and have interactions are studied.

Topicort and Lipitor drug interactions.

What are the common drug interactions of Topicort and Lipitor, by gender? *:

female:

  1. Application site vesicles (small bubble within a cell at application site)
  2. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  3. Arthropathy
  4. Asthenia (weakness)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Bladder cancer
  7. Breast cancer
  8. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  9. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  10. Cardiac failure congestive

male:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fibromyalgia (a long-term condition which causes pain all over the body)
  5. Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
  6. Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
  7. Myelopathy (any neurologic deficit related to the spinal cord)
  8. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  9. Pain
  10. Restless legs syndrome (a powerful urge to move your legs)

What are the common drug interactions of Topicort and Lipitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  2. Back pain
  3. Cardiac disorder
  4. Chest pain
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Arteriosclerosis (thickening and hardening of arteries)
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Cyst (a closed sac)
  9. Dyspepsia (indigestion)
  10. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

50-59:

  1. Lung disorder (lung disease)
  2. Muscle spasms (muscle contraction)
  3. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Night sweats (sweating in night)
  6. Obesity (having too much body fat)
  7. Oedema (fluid collection in tissue)
  8. Oedema peripheral (superficial swelling)
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Pain in extremity

60+:

  1. Abdominal pain upper
  2. Anaemia (lack of blood)
  3. Application site erythema (redness of the skin at application site)
  4. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  5. Arthralgia (joint pain)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Bladder cancer
  8. Breast cancer
  9. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  10. Cardiac failure

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 7 people, 24.14%
  2. Pain: 7 people, 24.14%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 20.69%
  4. High Blood Pressure: 5 people, 17.24%
  5. Depression: 4 people, 13.79%
  6. Diabetes: 4 people, 13.79%
  7. Rashes (redness): 4 people, 13.79%
  8. Insomnia (sleeplessness): 4 people, 13.79%
  9. Nausea And Vomiting: 4 people, 13.79%
  10. Fungal Infection: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Topicort and Lipitor?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Topicort and Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topicort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lipitor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on desoximetasone and atorvastatin calcium (the active ingredients of Topicort and Lipitor, respectively), and Topicort and Lipitor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: