Torsemide and Zanaflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Torsemide (torsemide) and Zanaflex (tizanidine hydrochloride). Common drug interactions include surgery among females and allergy to arthropod sting among males.

The phase IV clinical study analyzes what interactions people have when they take Torsemide and Zanaflex. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Torsemide?

Torsemide has active ingredients of torsemide. It is often used in high blood pressure. eHealthMe is studying from 33,072 Torsemide users. Check the latest studies of Torsemide.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.

On Jul, 07, 2026

80 people who take Torsemide and Zanaflex together, and have interactions are studied.

Torsemide and Zanaflex drug interactions.

What are the common drug interactions of Torsemide and Zanaflex, by gender? *:

female:

Surgery
Abdominal pain upper
Acute respiratory failure
Adverse event
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Atrial septal defect acquired (an abnormal opening between the left and right atria of the heart-acquired)
Bedridden
Cardiac failure congestive
Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

Allergy to arthropod sting
Arthropod sting (arthropod bite)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Paranasal sinus hypersecretion
Sinusitis (inflammation of sinus)
Chronic kidney disease
Multiple allergies (allergy to multiple agents)
Renal failure (kidney dysfunction)
Skin infection
Diarrhoea

What are the common drug interactions of Torsemide and Zanaflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Atrial septal defect acquired (an abnormal opening between the left and right atria of the heart-acquired)
Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
Injection site pain

40-49:

Pneumonia
Adverse drug reaction
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Fatigue (feeling of tiredness)
Infusion site bruising
Infusion site pain
Post procedural discharge
Sinusitis (inflammation of sinus)
Constipation

50-59:

Infusion site swelling
Injection site warmth
Lower limb fracture
Nephrolithiasis (calculi in the kidneys)
Post procedural discharge
Renal failure (kidney dysfunction)
Sinusitis (inflammation of sinus)
Skin discolouration (change of skin colour)
Somnolence (a state of near-sleep, a strong desire for sleep)
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Flushing (the warm, red condition of human skin)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Depression
Dysphonia (speech disorder attributable to a disorder of phonation)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypoaesthesia (reduced sense of touch or sensation)
Infection
Infusion site haemorrhage (bleeding from infusion site)
Infusion site swelling
Lyme disease (a bacterial infection that is spread to humans by infected ticks)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 16 people, 20.00%
Immunodeficiency Common Variable: 11 people, 13.75%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 12.50%
Depression: 7 people, 8.75%
Stress And Anxiety: 6 people, 7.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.50%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 6.25%
Pain: 5 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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