Trandolapril and Lortab drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trandolapril (trandolapril) and Lortab (acetaminophen; hydrocodone bitartrate). Common drug interactions include thrombotic stroke among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Trandolapril and Lortab. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Trandolapril?

Trandolapril has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 2,682 Trandolapril users. Check the latest studies of Trandolapril.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

On Jul, 09, 2026

26 people who take Trandolapril and Lortab together, and have interactions are studied.

Trandolapril and Lortab drug interactions.

What are the common drug interactions of Trandolapril and Lortab, by gender? *:

female:

Thrombotic stroke (stroke due to clot formation)
Transverse sinus thrombosis (a blood clot in transverse sinus)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fear of pregnancy
Nightmare (unpleasant dream)
Pain in extremity
Stress
Alopecia (absence of hair from areas of the body)

male:

Constipation
Swelling
Aspartate aminotransferase increased
Blood magnesium decreased
Cellulitis (infection under the skin)
Clavicle fracture
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
Face oedema (swelling of face)

What are the common drug interactions of Trandolapril and Lortab, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
General physical health deterioration (weak health status)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Injury
Pulmonary embolism (blockage of the main artery of the lung)
Thrombotic stroke (stroke due to clot formation)

40-49:

Face oedema (swelling of face)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Gingival bleeding (bleeding gums)
Gingival oedema (swelling of gums)
Gynaecomastia (enlargement of the gland tissue of the male breast)
Haematemesis (vomiting of blood)
Induration (thickening of tissue)
Infection
Irritable bowel syndrome
Jaw fracture

50-59:

n/a

60+:

Swelling
Constipation
Skin lesion
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
Anaemia (lack of blood)
Aortic valve disease
Asthenia (weakness)
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 23.08%
Hyperkalemia (damage to or disease of the kidney): 6 people, 23.08%
Immunodeficiency Common Variable: 5 people, 19.23%
Premenstrual Syndrome: 3 people, 11.54%
Nausea (feeling of having an urge to vomit): 3 people, 11.54%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 11.54%
Headache (pain in head): 3 people, 11.54%
Asthma: 3 people, 11.54%
Acne (skin problems that cause pimples): 3 people, 11.54%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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