Transderm scop and Zanaflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Transderm scop (scopolamine) and Zanaflex (tizanidine hydrochloride). Common drug interactions include milia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Transderm scop and Zanaflex. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Transderm scop?

Transderm scop has active ingredients of scopolamine. It is often used in motion sickness. eHealthMe is studying from 3,011 Transderm scop users. Check the latest studies of Transderm scop.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.

On Aug, 09, 2026

28 people who take Transderm scop and Zanaflex together, and have interactions are studied.

Transderm scop and Zanaflex drug interactions.

What are the common drug interactions of Transderm Scop and Zanaflex, by gender? *:

female:

Milia (dead skin becomes trapped in small pockets at the surface of the skin or mouth)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Urinary tract infection
Headache (pain in head)
Sinusitis (inflammation of sinus)
Blood pressure fluctuation
Hypoglycaemia (deficiency of glucose in the bloodstream)
Intervertebral disc protrusion (spinal disc protrusion)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Syncope (loss of consciousness with an inability to maintain postural tone)

male:

Abdominal pain
Blood pressure increased
Muscle atrophy (a decrease in the mass of the muscle)
Neoplasm (tumour)
Oral pain
Rash
Surgery
Thrombosis (formation of a blood clot inside a blood vessel)
Urticaria (rash of round, red welts on the skin that itch intensely)
Viral infection

What are the common drug interactions of Transderm Scop and Zanaflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Burning sensation
Application site burn
Application site discolouration
Application site erythema (redness of the skin at application site)
Application site exfoliation (application site removal of the oldest dead skin cells on the skin's outermost surface)
Application site irritation
Arthralgia (joint pain)
Catheter site infection (infection at the site of insertion)
Death
Dehydration (dryness resulting from the removal of water)

30-39:

n/a

40-49:

Vitreous opacities (vitreous opacities generally develop as aging changes within the eye)
Vomiting
Wheezing (a high-pitched whistling sound made while you breath)
Abdominal discomfort
Abdominal pain
Activities of daily living impaired
Agitation (state of anxiety or nervous excitement)
Anxiety disorder
Arthralgia (joint pain)
Arthropathy

50-59:

Poor venous access
Scar
Skin striae (irregular areas of skin that look like bands, stripes, or lines)
Foot fracture
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Ligament rupture (tear in ligament)
Nasopharyngitis (inflammation of the nasopharynx)
Abdominal pain
Blood pressure fluctuation
Blood pressure increased

60+:

Brain stem infarction (brainstem stroke)
Breast cancer
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Head injury
Interstitial lung disease
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Road traffic accident
Type 2 diabetes mellitus

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 42.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 25.00%
Immunodeficiency Common Variable: 6 people, 21.43%
Nausea (feeling of having an urge to vomit): 4 people, 14.29%
Sleep Disorder: 3 people, 10.71%
Pain: 3 people, 10.71%
Constipation: 3 people, 10.71%
Weight Decreased: 2 people, 7.14%
Osteosarcoma Metastatic (a cancerous (malignant) bone tumour can spreads to other parts): 2 people, 7.14%
Nausea And Vomiting: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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