Tranxene and Vesicare drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tranxene (clorazepate dipotassium) and Vesicare (solifenacin succinate). Common drug interactions include diverticulitis among females and visual impairment among males.
The phase IV clinical study analyzes what interactions people have when they take Tranxene and Vesicare. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Tranxene?
Tranxene has active ingredients of clorazepate dipotassium. It is often used in stress and anxiety. eHealthMe is studying from 6,550 Tranxene users. Check the latest studies of Tranxene.
What is Vesicare?
Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.
14 people who take Tranxene and Vesicare together, and have interactions are studied.

What are the common drug interactions of Tranxene and Vesicare, by gender? *:
female:
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Drug ineffective
- Dysuria (painful or difficult urination)
- Flatulence (flatus expelled through the anus)
- Hallucination (an experience involving the perception of something not present)
- Interstitial lung disease
- Intervertebral disc disorder (spinal disc disorder)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
- Respiratory distress (difficulty in breathing)
male:
- Visual impairment
- Confusional state
What are the common drug interactions of Tranxene and Vesicare, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Hepatocellular injury (liver injury)
40-49:
n/a
50-59:
- Cystitis (inflammation of the wall of the bladder)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Intervertebral disc disorder (spinal disc disorder)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
60+:
- Visual impairment
- Bladder neoplasm (bladder tumour)
- Interstitial lung disease
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
- Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
- Colon cancer
- Confusional state
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Drug ineffective
What are the existing conditions these people have? *
- Constipation: 6 people, 42.86%
- Birth Control: 5 people, 35.71%
- Urinary Tract Infection: 1 person, 7.14%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 7.14%
- Pain: 1 person, 7.14%
- Osteomyelitis (infection of bone): 1 person, 7.14%
- Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 1 person, 7.14%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
- High Blood Cholesterol: 1 person, 7.14%
- Gait Disturbance: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Tranxene and Vesicare?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tranxene and Vesicare:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tranxene:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vesicare:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tranxene and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vesicare and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on clorazepate dipotassium and solifenacin succinate (the active ingredients of Tranxene and Vesicare, respectively), and Tranxene and Vesicare (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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