Trileptal and Captopril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trileptal (oxcarbazepine) and Captopril (captopril). Common drug interactions include hypotonia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Trileptal and Captopril. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

On Jul, 16, 2026

47 people who take Trileptal and Captopril together, and have interactions are studied.

Trileptal and Captopril drug interactions.

What are the common drug interactions of Trileptal and Captopril, by gender? *:

female:

Hypotonia (low muscle tone)
Lethargy (tiredness)
Leukocytosis (increased white blood cells)
Localised infection (infection at the single location)
Loss of consciousness
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Muscle twitching
Nasopharyngitis (inflammation of the nasopharynx)
Nodule (a growth of abnormal tissue)

male:

Anxiety
Muscular weakness (muscle weakness)
Asthma
Blood testosterone decreased
Drug ineffective
Feeling hot
Gastrointestinal motility disorder (abnormal intestinal contractions)
Pneumonia
Serum serotonin decreased
Surgery

What are the common drug interactions of Trileptal and Captopril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Gingival hypertrophy (overgrowth of gums)
Hyperplasia (enlargement of an organ or tissue)
Oral disorder (mouth disease)
Angiopathy (generic term for a disease of the blood vessels)
Nodule (a growth of abnormal tissue)
Pyogenic granuloma (small, raised, red bumps on the skin)

20-29:

n/a

30-39:

Blood testosterone decreased
Feeling hot
Gastrointestinal motility disorder (abnormal intestinal contractions)
Inappropriate antidiuretic hormone secretion
Lethargy (tiredness)
Serum serotonin decreased

40-49:

Hyperaemia (increase of blood flow to different tissues in the body)
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Xerosis (abnormal dryness of the skin or mucus membranes)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Nasopharyngitis (inflammation of the nasopharynx)
Pancreatitis (inflammation of pancreas)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Renal failure (kidney dysfunction)

50-59:

Confusional state
Fatigue (feeling of tiredness)
Full blood count decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate antidiuretic hormone secretion
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Prostration

60+:

Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Oedema (fluid collection in tissue)
Hallucination (an experience involving the perception of something not present)
Heart rate increased
Hydrocephalus (water on the brain)
Hypotonia (low muscle tone)
Leukocytosis (increased white blood cells)
Loss of consciousness
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 25.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 17.02%

* Approximation only. Some reports may have incomplete information.

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