Trulicity and Avandia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Avandia (rosiglitazone maleate). Common drug interactions include diabetic ketoacidosis among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Avandia. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 142,155 Avandia users. Check the latest studies of Avandia.

On Aug, 12, 2026

17 people who take Trulicity and Avandia together, and have interactions are studied.

Trulicity and Avandia drug interactions.

What are the common drug interactions of Trulicity and Avandia, by gender? *:

female:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hunger
Hypophagia (reduced food intake)
Injection site bruising
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Weight increased
Chronic kidney disease

male:

Blood glucose increased
Cardiovascular disorder (heart diseases)
Gait disturbance
Pain
Cough
Decreased appetite
Depression
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Drug ineffective
Nephrogenic anaemia (anaemia due to kidney disease)

What are the common drug interactions of Trulicity and Avandia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Abdominal pain
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)
Vomiting

60+:

Blood glucose increased
Diarrhoea
Bone density decreased
Bone pain
Chronic kidney disease
Emotional distress
Gait disturbance
Pain
Renal failure (kidney dysfunction)
Early satiety (feeling full before completing a normal sized meal)

What are the existing conditions these people have? *

Type 2 Diabetes: 8 people, 47.06%
High Blood Cholesterol: 5 people, 29.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 23.53%
High Blood Pressure: 3 people, 17.65%
Depression: 2 people, 11.76%
Hiv Infection: 2 people, 11.76%
Infection: 2 people, 11.76%
Pain: 2 people, 11.76%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 11.76%
Cardiac Disorder: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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