Trulicity and Cipro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include infusion site irritation among females and necrotising fasciitis among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Cipro. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

48 people who take Trulicity and Cipro together, and have interactions are studied.

What are the common drug interactions of Trulicity and Cipro, by gender? *:

female:

Infusion site irritation
Injection site discolouration
Injection site irritation
Injection site pruritus (severe itching at injection site)
Injection site rash
Irritable bowel syndrome
Joint dislocation (a joint position is changed from normal position)
Lethargy (tiredness)
Limb injury
Lipase increased

male:

Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Abscess limb (limb infection)
Anal abscess
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Cerebral thrombosis (blood clot in brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Trulicity and Cipro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Sepsis (a severe blood infection that can lead to organ failure and death)
Anal abscess
Cellulitis (infection under the skin)
Chills (felling of cold)
Nausea (feeling of having an urge to vomit)
Nerve injury
Pain
Pyrexia (fever)

50-59:

Abdominal discomfort
Abdominal pain
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Lipase increased
Malaise (a feeling of general discomfort or uneasiness)
Oropharyngeal pain
Pancreatitis (inflammation of pancreas)
Renal failure (kidney dysfunction)
Vomiting

60+:

Weight decreased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Therapeutic response unexpected
Abscess limb (limb infection)
Adverse event
Anaemia (lack of blood)
Asthma
Cellulitis (infection under the skin)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Cerebral thrombosis (blood clot in brain)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 9 people, 18.75%
Type 2 Diabetes: 5 people, 10.42%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 8.33%
Diabetes: 4 people, 8.33%
Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 4 people, 8.33%
Weight Decreased: 3 people, 6.25%
Hidradenitis (chronic disease of a type of sweat gland): 3 people, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.25%
Essential Thrombocythaemia (chronic blood cancer): 3 people, 6.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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