Truvada and Thiamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Truvada (emtricitabine; tenofovir disoproxil fumarate) and Thiamine (thiamine (vitamin b1)). Common drug interactions include gait disturbance among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Truvada and Thiamine. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.

On Jul, 26, 2026

66 people who take Truvada and Thiamine together, and have interactions are studied.

What are the common drug interactions of Truvada and Thiamine, by gender? *:

female:

Gait disturbance
Bone density decreased
Arthralgia (joint pain)
Fracture
Fractured sacrum
Hip fracture
Joint dislocation (a joint position is changed from normal position)
Joint injury
Nephropathy (damage to or disease of a kidney)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

male:

Emotional distress
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Tooth loss
Ankle fracture
Blood creatinine increased
Rib fracture
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Joint injury
Osteonecrosis (death of bone)

What are the common drug interactions of Truvada and Thiamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Emotional distress
Pain
Depression
Arthralgia (joint pain)
Fracture
Fractured sacrum
Gait disturbance
Hip fracture
Joint dislocation (a joint position is changed from normal position)

40-49:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus)
Drug hypersensitivity
Dysphagia (a condition in which swallowing is difficult or painful)
Extrapulmonary tuberculosis (tb which occurs in any other part of the body outside the lungs)
Genital herpes (herpes infection of genital)
Head injury
Hiv peripheral neuropathy (neurological complication of hiv infection)
Hypertension (high blood pressure)
Hyperthyroidism (over activity of the thyroid gland)

50-59:

Anxiety
Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Renal impairment (severely reduced kidney function)
Rib fracture
Chronic kidney disease

60+:

Emotional distress
Pain
Blood potassium decreased
Dysstasia (difficulty in standing)
Haemoglobin decreased
Multiple fractures
Quality of life decreased
Blood creatinine increased
Joint injury
Osteopenia (a condition where bone mineral density is lower than normal)

What are the existing conditions these people have? *

Pain: 6 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.09%
Fungal Infection: 5 people, 7.58%
Stress And Anxiety: 4 people, 6.06%
High Blood Pressure: 4 people, 6.06%
Hepatitis C: 4 people, 6.06%
Depression: 4 people, 6.06%
Constipation: 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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