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Asacol hd and Lexapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asacol hd (mesalamine) and Lexapro (escitalopram oxalate). Common drug interactions include hypertension among females and blood cholesterol increased among males.

The phase IV clinical study analyzes what interactions people have when they take Asacol hd and Lexapro. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Asacol hd?

Asacol hd has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 985 Asacol hd users. Check the latest studies of Asacol hd.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

On Jul, 26, 2026

26 people who take Asacol hd and Lexapro together, and have interactions are studied.

Asacol hd and Lexapro drug interactions.

What are the common drug interactions of Asacol Hd and Lexapro, by gender? *:

female:

  1. Hypertension (high blood pressure)
  2. Pain in extremity
  3. Arthralgia (joint pain)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. Herpes zoster
  8. Injection site pain
  9. Nausea (feeling of having an urge to vomit)
  10. Snoring

male:

  1. Blood cholesterol increased
  2. Diarrhoea
  3. Painful defaecation
  4. Pyrexia (fever)
  5. Abdominal pain lower
  6. Dizziness
  7. Fatigue (feeling of tiredness)
  8. Frequent bowel movements
  9. Gastrointestinal pain
  10. Haematochezia (passage of stools containing blood)

What are the common drug interactions of Asacol Hd and Lexapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood cholesterol increased
  2. Diarrhoea
  3. Dizziness
  4. Frequent bowel movements
  5. Haematochezia (passage of stools containing blood)
  6. Iron deficiency
  7. Painful defaecation
  8. Pyrexia (fever)

30-39:

  1. Injection site bruising
  2. Injection site erythema (redness at injection site)
  3. Injection site pruritus (severe itching at injection site)
  4. Injection site swelling
  5. Abdominal pain lower
  6. Blood cholesterol increased
  7. Diarrhoea
  8. Fatigue (feeling of tiredness)
  9. Gastrointestinal pain
  10. Injection site mass

40-49:

  1. Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop)
  2. Arthralgia (joint pain)
  3. Biliary cirrhosis primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver)
  4. Blood immunoglobulin g increased
  5. Blood potassium decreased
  6. Gallbladder injury
  7. Hepatitis viral
  8. Hyperlipidaemia (presence of excess lipids in the blood)
  9. Injection site reaction
  10. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Abdominal discomfort
  3. Abdominal pain upper
  4. Acne (skin problems that cause pimples)
  5. Adverse event
  6. Arthralgia (joint pain)
  7. Balance disorder
  8. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  9. Blood iron decreased
  10. Dizziness

60+:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Herpes zoster
  3. Ageusia (loss of taste functions of the tongue)
  4. Chest pain
  5. Decreased appetite
  6. Hypertension (high blood pressure)
  7. Injection site pain
  8. Nausea (feeling of having an urge to vomit)
  9. Pneumonia

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 34.62%
  2. Stress And Anxiety: 6 people, 23.08%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 19.23%
  4. Hypersensitivity: 4 people, 15.38%
  5. High Blood Pressure: 4 people, 15.38%
  6. High Blood Cholesterol: 4 people, 15.38%
  7. Insomnia (sleeplessness): 3 people, 11.54%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 11.54%
  9. Constipation: 3 people, 11.54%
  10. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Asacol hd and Lexapro?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Asacol hd and Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Asacol hd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Asacol hd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and escitalopram oxalate (the active ingredients of Asacol hd and Lexapro, respectively), and Asacol hd and Lexapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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