Tylenol w/ codeine no. 3 and Peg-intron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate) and Peg-intron (peginterferon alfa-2b). Common drug interactions include weight decreased among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine no. 3 and Peg-intron. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Peg-intron?

Peg-intron has active ingredients of peginterferon alfa-2b. eHealthMe is studying from 11,142 Peg-intron users. Check the latest studies of Peg-intron.



On Jul, 16, 2026

13 people who take Tylenol w/ codeine no. 3 and Peg-intron together, and have interactions are studied.

Tylenol w/ codeine no. 3 and Peg-intron drug interactions.

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Peg-Intron, by gender? *:

female:

  1. Weight decreased
  2. Asthenia (weakness)
  3. Nausea (feeling of having an urge to vomit)
  4. Vomiting
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Diarrhoea
  7. Fatigue (feeling of tiredness)
  8. Injection site erythema (redness at injection site)
  9. Suicidal ideation
  10. Anxiety

male:

  1. Chest pain
  2. Cryoglobulinaemia (blood contains large amounts of cryoglobulins - proteins)
  3. Red blood cell count decreased
  4. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  5. Rib fracture
  6. Suicidal ideation
  7. Upper respiratory tract infection
  8. Visual disturbance
  9. Depression
  10. Dizziness

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Peg-Intron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  2. Bacterial infection
  3. Cellulitis (infection under the skin)
  4. Chest pain
  5. Constipation
  6. Cough
  7. Crying
  8. Culture wound positive
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Epidermal necrosis (skin condition that is usually caused by a reaction to drugs)

40-49:

  1. Injection site induration
  2. Injection site pain

50-59:

  1. Weight decreased
  2. Asthenia (weakness)
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Burning sensation
  5. Decreased appetite
  6. Depression
  7. Disturbance in attention
  8. Dry mouth
  9. Epistaxis (bleed from the nose)
  10. Fall

60+:

n/a

What are the existing conditions these people have? *

  1. Hepatitis C: 10 people, 76.92%
  2. Joint Pain: 1 person, 7.69%
  3. Hereditary Haemorrhagic Telangiectasia (hereditary -development of multiple abnormalities in the blood vessels): 1 person, 7.69%
  4. Hepatitis B: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine no. 3 and Peg-intron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tylenol w/ codeine no. 3 and Peg-intron:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine no. 3:

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Browse all side effects of Peg-intron:

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Browse all interactions between Tylenol w/ codeine no. 3 and drugs from A to Z:

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Browse all interactions between Peg-intron and drugs from A to Z:

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How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and peginterferon alfa-2b (the active ingredients of Tylenol w/ codeine no. 3 and Peg-intron, respectively), and Tylenol w/ codeine no. 3 and Peg-intron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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