Tylenol and Asacol hd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol (acetaminophen) and Asacol hd (mesalamine). Common drug interactions include injection site pain among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol and Asacol hd. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,310 Tylenol users. Check the latest studies of Tylenol.

What is Asacol hd?

Asacol hd has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 985 Asacol hd users. Check the latest studies of Asacol hd.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

33 people who take Tylenol and Asacol hd together, and have interactions are studied.

Tylenol and Asacol hd drug interactions.

What are the common drug interactions of Tylenol and Asacol Hd, by gender? *:

female:

Injection site pain
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Diarrhoea
Haematochezia (passage of stools containing blood)
Infusion related reaction
Injection site bruising
Injection site swelling
Nasopharyngitis (inflammation of the nasopharynx)
Pregnancy
Pyrexia (fever)

male:

Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Frequent bowel movements
Haematochezia (passage of stools containing blood)
Drug ineffective
Prostatic specific antigen increased
Sinusitis (inflammation of sinus)

What are the common drug interactions of Tylenol and Asacol Hd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective

30-39:

Abdominal pain
Drug ineffective
Injection site swelling
Nasopharyngitis (inflammation of the nasopharynx)
Pregnancy
Thyroid cancer
Drug specific antibody present
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Infusion related reaction

40-49:

Abscess intestinal (collections of pus-intestinal)
Arthralgia (joint pain)
Back pain
Haematochezia (passage of stools containing blood)
Injection site bruising
Mucous stools (mucous with stool)
Osteonecrosis (death of bone)
Sinusitis (inflammation of sinus)

50-59:

Injection site pain
Pyrexia (fever)
Abdominal abscess (collection of pus in abdomen)
Abdominal distension
Abscess (pus)
Cataract (clouding of the lens inside the eye)
Chest discomfort
Chest pain
Chills (felling of cold)
Decreased appetite

60+:

Flatulence (flatus expelled through the anus)
Frequent bowel movements
Haematochezia (passage of stools containing blood)
Dementia (madness)
Fall
Head injury
Subdural haematoma (blood collects between the skull and the surface of the brain)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 51.52%
Stress And Anxiety: 4 people, 12.12%
Headache (pain in head): 4 people, 12.12%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 3 people, 9.09%
Upper Respiratory Tract Infection: 3 people, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 9.09%
Hyperglycemia (high blood sugar): 3 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.09%
Type 1 Diabetes: 2 people, 6.06%
Sedation: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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