Tysabri and Erbitux drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tysabri (natalizumab) and Erbitux (cetuximab). Common drug interactions include diarrhoea among females and metastatic squamous cell carcinoma among males.
The phase IV clinical study analyzes what interactions people have when they take Tysabri and Erbitux. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Tysabri?
Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.
What is Erbitux?
Erbitux has active ingredients of cetuximab. It is often used in cancer. eHealthMe is studying from 19,276 Erbitux users. Check the latest studies of Erbitux.
14 people who take Tysabri and Erbitux together, and have interactions are studied.

What are the common drug interactions of Tysabri and Erbitux, by gender? *:
female:
- Diarrhoea
- Thrombocytopenia (decrease of platelets in blood)
- Rash
- Febrile neutropenia (fever with reduced white blood cells)
- Ascites (accumulation of fluid in the abdominal cavity)
- Blood creatine phosphokinase increased
- Blood creatinine increased
- Fatigue (feeling of tiredness)
- Infusion related reaction
- Neutropenia (an abnormally low number of neutrophils)
male:
- Metastatic squamous cell carcinoma (cancer of squamous cells spreads to other part)
- Back pain
- Muscular weakness (muscle weakness)
- Nausea (feeling of having an urge to vomit)
- Pain in extremity
- Poor venous access
- Stress
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Laryngeal mass (mass on larynx)
What are the common drug interactions of Tysabri and Erbitux, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Infusion related reaction
- Neck pain
- Pruritus (severe itching of the skin)
- Rash
30-39:
n/a
40-49:
- Dehydration (dryness resulting from the removal of water)
- Device related infection
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
- Pyrexia (fever)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
50-59:
- Metastatic squamous cell carcinoma (cancer of squamous cells spreads to other part)
- Laryngeal mass (mass on larynx)
- Vocal cord thickening
- Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
- Fatigue (feeling of tiredness)
- Groin abscess (pus in groin)
- Headache (pain in head)
- Liver disorder (liver diseases)
- Lung infection
- Migraine (headache)
60+:
- Diarrhoea
- Fatigue (feeling of tiredness)
- Memory impairment
- Muscular weakness (muscle weakness)
- Nausea (feeling of having an urge to vomit)
- Pain in extremity
- Poor venous access
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Febrile neutropenia (fever with reduced white blood cells)
What are the existing conditions these people have? *
- Colon Cancer: 4 people, 28.57%
- Oral Cancer (mouth cancer): 2 people, 14.29%
- Sleep Disorder: 1 person, 7.14%
- Pain: 1 person, 7.14%
- Migraine (headache): 1 person, 7.14%
- Metastases To Lung (cancer spreads to lung): 1 person, 7.14%
- Gait Disturbance: 1 person, 7.14%
- Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Tysabri and Erbitux?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tysabri and Erbitux:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tysabri:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Erbitux:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tysabri and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Erbitux and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta D, Shukla P, Bisht SS, Bhatt ML, Pant MC, Srivastava K, "Deep vein and artery thrombosis associated with cetuximab-based chemoradiotherapy", Indian journal of pharmacology, 2011 Jan .
- Gupta D, Shukla P, Bisht SS, Bhatt ML, Pant MC, Srivastava K, "Deep vein and artery thrombosis associated with cetuximab-based chemoradiotherapy", Indian journal of pharmacology, 2011 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on natalizumab and cetuximab (the active ingredients of Tysabri and Erbitux, respectively), and Tysabri and Erbitux (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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