Uloric and Invokana drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uloric (febuxostat) and Invokana (canagliflozin). Common drug interactions include abdominal discomfort among females and back disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Uloric and Invokana. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

What is Invokana?

Invokana has active ingredients of canagliflozin. It is often used in diabetes. eHealthMe is studying from 29,937 Invokana users. Check the latest studies of Invokana.

On Jul, 09, 2026

19 people who take Uloric and Invokana together, and have interactions are studied.

What are the common drug interactions of Uloric and Invokana, by gender? *:

female:

Abdominal discomfort
Dyspepsia (indigestion)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperchlorhydria (gastric acid levels are higher in stomach)
Arthralgia (joint pain)
Asthma
Chronic kidney disease
Death
Dizziness
Drug ineffective

male:

Back disorder
Back injury
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Blood glucose decreased
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Chronic kidney disease
Drug ineffective
Oedema (fluid collection in tissue)

What are the common drug interactions of Uloric and Invokana, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

Chronic kidney disease
Acute myocardial infarction (acute heart attack)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Renal failure (kidney dysfunction)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

60+:

Back disorder
Back injury
Blood glucose increased
Death
Dizziness
Drug ineffective
Dyspepsia (indigestion)
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperchlorhydria (gastric acid levels are higher in stomach)

What are the existing conditions these people have? *

Type 2 Diabetes: 7 people, 36.84%
High Blood Pressure: 5 people, 26.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 26.32%
High Blood Cholesterol: 4 people, 21.05%
Parkinson's Disease: 4 people, 21.05%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 21.05%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 15.79%
Stress And Anxiety: 2 people, 10.53%
Muscle Spasms (muscle contraction): 2 people, 10.53%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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