Acetaminophen and Psychiatric symptom - a phase IV clinical study of FDA data

Summary:

Psychiatric symptom is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Folic Acid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Psychiatric symptom when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Psychiatric symptom?

Psychiatric symptom is found to be associated with 639 drugs and 755 conditions by eHealthMe. Check the latest studies of Psychiatric symptom.

On Jul, 09, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 75 people (0.04%) have Psychiatric symptom.

Could Acetaminophen cause Psychiatric symptom?

Among these 75 people:

How long have people been on Acetaminophen when they have Psychiatric symptom? *

What is the gender of people who have Psychiatric symptom when taking Acetaminophen? *

female: 83.08 %
male: 16.92 %

What is the age of people who have Psychiatric symptom when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

What are other side effects people have besides Psychiatric symptom? *

Fall: 31 people, 41.33%
Stress And Anxiety: 31 people, 41.33%
Fatigue (feeling of tiredness): 30 people, 40.00%
Joint Pain: 28 people, 37.33%
Malaise (a feeling of general discomfort or uneasiness): 27 people, 36.00%
Urinary Tract Infection: 22 people, 29.33%
Weakness: 21 people, 28.00%
General Physical Health Deterioration (weak health status): 21 people, 28.00%
Drug Ineffective: 20 people, 26.67%
Weight Decreased: 20 people, 26.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 25 people, 33.33%
Depression: 9 people, 12.00%
Multiple Myeloma (cancer of the plasma cells): 8 people, 10.67%
Fever: 6 people, 8.00%
Bone Pain: 6 people, 8.00%
Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 8.00%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 5 people, 6.67%
Inflammation: 5 people, 6.67%
Ill-Defined Disorder: 5 people, 6.67%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 5 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Psychiatric symptom?

- Check whether Psychiatric symptom is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psychiatric symptom:

Psychiatric symptom (639 drugs)

Browse all the conditions that are associated with Psychiatric symptom:

Psychiatric symptom (755 conditions)

Related publications that referenced our studies

Moftah NH, Kamel AM, Attia HM, El-Baz MZ, El–Moty HM, "Skin diseases in patients with primary psychiatric conditions: a hospital based study", Journal of epidemiology and global health, 2013 Sep .
Moftah NH, Kamel AM, Attia HM, El-Baz MZ, El–Moty HM, "Skin diseases in patients with primary psychiatric conditions: a hospital based study", Journal of epidemiology and global health, 2013 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.