Ultram and Benlysta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ultram (tramadol hydrochloride) and Benlysta (belimumab). Common drug interactions include dizziness among females and dizziness among males.
The phase IV clinical study analyzes what interactions people have when they take Ultram and Benlysta. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Ultram?
Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.
What is Benlysta?
Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.
21 people who take Ultram and Benlysta together, and have interactions are studied.

What are the common drug interactions of Ultram and Benlysta, by gender? *:
female:
- Dizziness
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Depression
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Fatigue (feeling of tiredness)
- General physical health deterioration (weak health status)
- Injury
- Urinary tract infection
male:
- Dizziness
- Drug administration error
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Cellulitis (infection under the skin)
- Injection site haematoma (localized swelling filled with blood at injection site)
- Insomnia (sleeplessness)
- Oedema (fluid collection in tissue)
- Urinary tract infection
What are the common drug interactions of Ultram and Benlysta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Dizziness
- Drug administration error
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
10-19:
n/a
20-29:
n/a
30-39:
- Chest discomfort
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Feeling hot
- Flushing (the warm, red condition of human skin)
- Hyperhidrosis (abnormally increased sweating)
- Throat tightness
40-49:
- Dizziness
- Influenza like illness
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Nail disorder (disease of nail)
- Adverse drug reaction
- Anxiety
- Arthralgia (joint pain)
- Blood potassium decreased
50-59:
- Depression
- Nausea (feeling of having an urge to vomit)
- Urinary tract infection
- Balance disorder
- Contusion (a type of hematoma of tissue in which capillaries)
- Dizziness
- Drug administration error
- Dyspnoea (difficult or laboured respiration)
- Fall
- Headache (pain in head)
60+:
- Anxiety
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Depression
- Diarrhoea
- Dressler's syndrome (inflammation of the sac surrounding the hear)
- Drug hypersensitivity
- Headache (pain in head)
- Insomnia (sleeplessness)
- Nausea (feeling of having an urge to vomit)
- Renal disorder (kidney disease)
* Approximation only. Some reports may have incomplete information.
Do you take Ultram and Benlysta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ultram and Benlysta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ultram:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Benlysta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ultram and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Benlysta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on tramadol hydrochloride and belimumab (the active ingredients of Ultram and Benlysta, respectively), and Ultram and Benlysta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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