Ultram and Travatan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ultram (tramadol hydrochloride) and Travatan (travoprost). Common drug interactions include transient ischaemic attack among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Ultram and Travatan. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

What is Travatan?

Travatan has active ingredients of travoprost. It is often used in glaucoma. eHealthMe is studying from 13,103 Travatan users. Check the latest studies of Travatan.



On Jul, 05, 2026

42 people who take Ultram and Travatan together, and have interactions are studied.

Ultram and Travatan drug interactions.

What are the common drug interactions of Ultram and Travatan, by gender? *:

female:

  1. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  2. Renal failure (kidney dysfunction)
  3. Urinary tract infection
  4. Vision blurred
  5. Activities of daily living impaired
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Bone pain
  9. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  10. Cerebral infarction (less blood supply to brain resulting tissue damage)

male:

  1. Chronic kidney disease
  2. Enterocolitis infectious
  3. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  4. Multiple allergies (allergy to multiple agents)
  5. Osteoporosis (bones weak and more likely to break)
  6. Plasma cell myeloma (cancer that begins in plasma cells)
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Skin cancer
  9. Tendon rupture (tear of tendon)
  10. Wound dehiscence (a surgical incision reopens either internally or externally)

What are the common drug interactions of Ultram and Travatan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)

60+:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Dizziness
  4. Dyspnoea (difficult or laboured respiration)
  5. Dysuria (painful or difficult urination)
  6. Enterocolitis infectious
  7. Eye haemorrhage (bleeding in the eye)
  8. Fall
  9. Febrile neutropenia (fever with reduced white blood cells)
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 14.29%
  2. Multiple Myeloma (cancer of the plasma cells): 5 people, 11.90%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 11.90%
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 9.52%
  5. High Blood Cholesterol: 4 people, 9.52%
  6. Stress And Anxiety: 3 people, 7.14%
  7. Nausea (feeling of having an urge to vomit): 3 people, 7.14%
  8. High Blood Pressure: 3 people, 7.14%
  9. Diabetes: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Ultram and Travatan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ultram and Travatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Travatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ultram and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Travatan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride and travoprost (the active ingredients of Ultram and Travatan, respectively), and Ultram and Travatan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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