Urocit-k and Paxil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Urocit-k (potassium citrate) and Paxil (paroxetine hydrochloride). Common drug interactions include femur fracture among females and cardiac arrest among males.
The phase IV clinical study analyzes what interactions people have when they take Urocit-k and Paxil. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Urocit-k?
Urocit-k has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 708 Urocit-k users. Check the latest studies of Urocit-k.
What is Paxil?
Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.
16 people who take Urocit-k and Paxil together, and have interactions are studied.

What are the common drug interactions of Urocit-K and Paxil, by gender? *:
female:
- Femur fracture
- Hip fracture
- Injection site pruritus (severe itching at injection site)
- Anaemia of malignant disease
- Asthenia (weakness)
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Decreased appetite
- Diarrhoea
- Fatigue (feeling of tiredness)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
male:
- Cardiac arrest
- Cardiac disorder
- Suicidal ideation
- Cardiac tamponade (fluid accumulates in heart covering)
- Emotional distress
- Hypersexuality
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
- Left ventricular failure (left ventricle fails to contract forcefully)
- Obsessive-compulsive personality disorder (a mental health condition in which a person is preoccupied with rules, orderliness, and control)
- Pathological gambling
What are the common drug interactions of Urocit-K and Paxil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Constipation
- Cough
- Cytogenetic abnormality
- Decreased activity
- Decreased appetite
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diarrhoea
- Drug intolerance (drug sensitivity)
- Duodenal polyp (duodenal epithelial tumours)
50-59:
- Back pain
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Bullous lung disease
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Decreased appetite
- Diarrhoea
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Gait disturbance
60+:
- Cardiac arrest
- Cardiac disorder
- Cardiac tamponade (fluid accumulates in heart covering)
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
- Left ventricular failure (left ventricle fails to contract forcefully)
- Right ventricular failure (right half of the heart fails to work)
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 12 people, 75.00%
- Bone Density Decreased: 7 people, 43.75%
- Bone Loss: 5 people, 31.25%
- High Blood Pressure: 2 people, 12.50%
- Sleep Apnea Syndrome: 1 person, 6.25%
- Blood Homocysteine Increased: 1 person, 6.25%
- Diabetes: 1 person, 6.25%
- Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 6.25%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
- Headache (pain in head): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Urocit-k and Paxil?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Urocit-k and Paxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Urocit-k:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Paxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Urocit-k and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paxil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on potassium citrate and paroxetine hydrochloride (the active ingredients of Urocit-k and Paxil, respectively), and Urocit-k and Paxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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