Valacyclovir and Horizant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir (valacyclovir hydrochloride) and Horizant (gabapentin enacarbil). Common drug interactions include neuralgia among females and memory impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir and Horizant. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

What is Horizant?

Horizant has active ingredients of gabapentin enacarbil. It is often used in restless leg syndrome. eHealthMe is studying from 2,051 Horizant users. Check the latest studies of Horizant.

On Jul, 18, 2026

27 people who take Valacyclovir and Horizant together, and have interactions are studied.

Valacyclovir and Horizant drug interactions.

What are the common drug interactions of Valacyclovir and Horizant, by gender? *:

female:

Neuralgia (pain in one or more nerves)
Oral herpes (viral infection of mouth)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Somnolence (a state of near-sleep, a strong desire for sleep)
Adjustment disorder
Arthralgia (joint pain)
Asthenia (weakness)
Atrophy (wasting away of a part of the body)
Balance disorder
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)

male:

Memory impairment
Nightmare (unpleasant dream)
Pain
Adverse drug reaction

What are the common drug interactions of Valacyclovir and Horizant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Cystitis interstitial (unknown cause characterized by bladder pain)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Panic attack
Snoring

20-29:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

30-39:

Dizziness
Renal glycosuria (simple sugar glucose is excreted in the urine)
Shoulder operation
Urine ketone body present

40-49:

Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Hepatic steatosis (fatty liver disease)
Petit mal epilepsy (absence seizure)
Thyroid disorder (thyroid diseases)
Oral herpes (viral infection of mouth)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Adjustment disorder

50-59:

Breast mass

60+:

Memory impairment
Nightmare (unpleasant dream)
Pain
Balance disorder
Dizziness
Hemiparesis (weakness on one side of the body)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 48.15%
Multiple Myeloma (cancer of the plasma cells): 3 people, 11.11%
Pain: 2 people, 7.41%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.41%
Insomnia (sleeplessness): 2 people, 7.41%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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