Valcyte and Spironolactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valcyte (valganciclovir hydrochloride) and Spironolactone (spironolactone). Common drug interactions include urinary tract infection among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Valcyte and Spironolactone. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

On Jul, 16, 2026

65 people who take Valcyte and Spironolactone together, and have interactions are studied.

Valcyte and Spironolactone drug interactions.

What are the common drug interactions of Valcyte and Spironolactone, by gender? *:

female:

Urinary tract infection
Blood sodium decreased
Catatonia (unresponsive to external stimuli)
Drug ineffective
Drug level above therapeutic
Oedema peripheral (superficial swelling)
Abdominal pain
Abdominal pain lower
Acquired pyloric stenosis (a condition that causes severe projectile non-bilious vomiting in the first few months of life)
Acute respiratory distress syndrome

male:

Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Thrombocytopenia (decrease of platelets in blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dementia (madness)
Dyspnoea (difficult or laboured respiration)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Loss of consciousness
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

What are the common drug interactions of Valcyte and Spironolactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Ascites (accumulation of fluid in the abdominal cavity)
Blood sodium decreased
Catatonia (unresponsive to external stimuli)
Drug ineffective
Drug level above therapeutic
Oedema peripheral (superficial swelling)

20-29:

Abdominal pain upper
Local swelling (swelling at the site of some application of substance or injury)
Swelling face

30-39:

Cardiomegaly (increased size of heart than normal)
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain upper
Alcohol use
Anuria (failure of the kidneys to produce urine)
Arrhythmia (irregular heartbeat)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Atelectasis (partial or complete collapse of the lung)

40-49:

Hypotension (abnormally low blood pressure)
Abdominal wall infection
Ascites (accumulation of fluid in the abdominal cavity)
Cholangitis (infection of the bile duct)
Fluid overload (too much fluid in the blood)
General physical health deterioration (weak health status)
Liver abscess (pus in liver)
Pneumonia
Puncture site pain
Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

Hepatic failure (liver failure)
Liver transplant rejection (failure of liver transplant)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abnormal behaviour
Blood cortisol decreased
Blood immunoglobulin g decreased
Decreased appetite
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Hyperlipidaemia (presence of excess lipids in the blood)

60+:

Pneumonia
Chronic kidney disease
Hypotension (abnormally low blood pressure)
Loss of consciousness
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

What are the existing conditions these people have? *

High Blood Pressure: 17 people, 26.15%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 16.92%
Pain: 8 people, 12.31%
Hepatitis C: 7 people, 10.77%
Constipation: 7 people, 10.77%
Infection: 6 people, 9.23%
Hiv Infection: 6 people, 9.23%
Cough: 6 people, 9.23%
Renal Disorder (kidney disease): 5 people, 7.69%
Liver Disorder (liver diseases): 5 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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