Valerian and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valerian (valerian) and Seroquel (quetiapine fumarate). Common drug interactions include osteoarthritis among females and hangover among males.

The phase IV clinical study analyzes what interactions people have when they take Valerian and Seroquel. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Valerian?

Valerian has active ingredients of valerian. It is often used in insomnia. eHealthMe is studying from 1,271 Valerian users. Check the latest studies of Valerian.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,287 Seroquel users. Check the latest studies of Seroquel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

33 people who take Valerian and Seroquel together, and have interactions are studied.

Valerian and Seroquel drug interactions.

What are the common drug interactions of Valerian and Seroquel, by gender? *:

female:

Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Initial insomnia (feeling of inadequate or poor-quality sleep)
Weight increased
Anaemia (lack of blood)
Clostridial infection (infectious conditions by clostridium bacteria)
Diarrhoea
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Restless legs syndrome (a powerful urge to move your legs)
Ear infection

male:

Hangover
Abnormal sensation in eye
Drug level decreased
Parkinson's disease
Therapeutic response unexpected
Weight decreased
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Heart rate increased
Muscle spasms (muscle contraction)
Substance abuse

What are the common drug interactions of Valerian and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Disturbance in attention
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

Arrhythmia (irregular heartbeat)
Dyskinesia (abnormality or impairment of voluntary movement)
Muscle rigidity (muscle stiffness)
Paralysis
Respiratory disorder (respiratory disease)
Secretion discharge
Blood creatine increased
Blood pressure systolic decreased
Hypotension (abnormally low blood pressure)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

n/a

50-59:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hangover
Heart rate increased
Muscle spasms (muscle contraction)
Swelling
Temporal arteritis (inflammation and damage to blood vessels that supply the head area)
Drug level decreased
Clostridial infection (infectious conditions by clostridium bacteria)
Diarrhoea
Abnormal sensation in eye

60+:

Ear infection
Sinusitis (inflammation of sinus)
Cellulitis (infection under the skin)
Urinary tract infection
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Fear of disease
Tendonitis (a condition that causes pain and swelling of tendons)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 42.42%
Sleep Disorder: 7 people, 21.21%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 15.15%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 9.09%
Breast Cancer: 3 people, 9.09%
Parkinson's Disease: 2 people, 6.06%
Arterial Rupture: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Valerian and Seroquel?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously