Valium and Zebeta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valium (diazepam) and Zebeta (bisoprolol fumarate). Common drug interactions include fatigue among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Valium and Zebeta. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Zebeta?

Zebeta has active ingredients of bisoprolol fumarate. It is often used in high blood pressure. eHealthMe is studying from 1,734 Zebeta users. Check the latest studies of Zebeta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 25, 2026

15 people who take Valium and Zebeta together, and have interactions are studied.

Valium and Zebeta drug interactions.

What are the common drug interactions of Valium and Zebeta, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Leukocytosis (increased white blood cells)
  3. Myalgia (muscle pain)
  4. Nausea (feeling of having an urge to vomit)
  5. Pneumonia
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Aggression
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Arthralgia (joint pain)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

  1. Weight decreased
  2. Dysuria (painful or difficult urination)
  3. Pain
  4. Prostatic disorder

What are the common drug interactions of Valium and Zebeta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Blood cholesterol increased
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Glaucoma (increased fluid pressure in the eye with vision loss)
  6. Neuropathy peripheral (surface nerve damage)
  7. Purpura senile (skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath)
  8. Renal failure (kidney dysfunction)
  9. Resorption bone increased
  10. Tarsal tunnel syndrome (a condition that is caused by compression of the tibial nerve or its associated branches as the nerve)

40-49:

  1. Aggression
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Insomnia (sleeplessness)
  4. Memory impairment
  5. Night sweats (sweating in night)
  6. Nightmare (unpleasant dream)
  7. Screaming (a long loud piercing cry)
  8. Sleep disorder
  9. Suicidal ideation
  10. Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

  1. Death
  2. Diplopia (double vision)
  3. Fatigue (feeling of tiredness)
  4. Muscle cramp (painful sensation caused by muscle contraction)
  5. Pneumonia
  6. Vision blurred

60+:

  1. Asthenia (weakness)
  2. Blood creatinine increased
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Arthralgia (joint pain)
  5. Back pain
  6. Blood glucose increased
  7. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  8. Chest pain
  9. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  10. Confusional state

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 3 people, 20.00%
  2. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 2 people, 13.33%
  3. Blood Testosterone Decreased: 2 people, 13.33%
  4. Pain: 2 people, 13.33%
  5. Muscle Spasms (muscle contraction): 2 people, 13.33%
  6. Dyspnea (difficult or laboured breathing): 2 people, 13.33%
  7. High Blood Cholesterol: 1 person, 6.67%
  8. Back Pain: 1 person, 6.67%
  9. Blood Disorder: 1 person, 6.67%
  10. Blood Pressure Abnormal: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Valium and Zebeta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valium and Zebeta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zebeta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zebeta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diazepam and bisoprolol fumarate (the active ingredients of Valium and Zebeta, respectively), and Valium and Zebeta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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