Valtrex and Vancomycin hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valtrex (valacyclovir hydrochloride) and Vancomycin hcl (vancomycin hydrochloride). Common drug interactions include chronic sinusitis among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Valtrex and Vancomycin hcl. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

On Jul, 11, 2026

43 people who take Valtrex and Vancomycin hcl together, and have interactions are studied.

Valtrex and Vancomycin hcl drug interactions.

What are the common drug interactions of Valtrex and Vancomycin Hcl, by gender? *:

female:

Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Dental caries
Depression
Device related infection
Diabetic foot
Diarrhoea
Dysthymic disorder (mild chronic depression disorder)
Dysuria (painful or difficult urination)
Ear pain

male:

Drug ineffective
Multi-organ failure (multisystem organ failure)
Enterobacter test positive
Eschar (dead tissue that falls off (sheds) from healthy skin)
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Respiratory distress (difficulty in breathing)
Septic shock (shock due to blood infection)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

What are the common drug interactions of Valtrex and Vancomycin Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

10-19:

n/a

20-29:

Neoplasm progression (growth of tumour)
Anaemia (lack of blood)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Dyspnoea (difficult or laboured respiration)
Injury
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pain
Platelet count decreased
Pleural effusion (water on the lungs)
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

Drug ineffective
Cardiac failure congestive
Death
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Febrile neutropenia (fever with reduced white blood cells)
Multi-organ failure (multisystem organ failure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Cardiac arrest
Cardiomegaly (increased size of heart than normal)

40-49:

Diarrhoea
Dysuria (painful or difficult urination)
Ear pain
Emotional distress
External ear disorder
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Lacrimation increased

50-59:

Renal failure acute (rapid kidney dysfunction)
Autoimmune hepatitis
Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Hypergammaglobulinaemia benign monoclonal (elevated levels of gamma globulin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Transaminases increased
Blood creatinine increased
Blood pressure increased
Clostridium difficile toxin test positive

60+:

Pleural effusion (water on the lungs)
Acute myocardial infarction (acute heart attack)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Renal failure (kidney dysfunction)
Respiratory distress (difficulty in breathing)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Wound infection staphylococcal
Cholangitis acute (rapid infection of bile duct)

What are the existing conditions these people have? *

Stress And Anxiety: 9 people, 20.93%
Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 16.28%
High Blood Pressure: 5 people, 11.63%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 9.30%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 9.30%
Localised Infection (infection at the single location): 4 people, 9.30%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 9.30%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 9.30%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.98%
Nausea (feeling of having an urge to vomit): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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