Vancomycin hcl and Claforan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and Claforan (cefotaxime sodium). Common drug interactions include eye irritation among females and ileus among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and Claforan. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is Claforan?

Claforan has active ingredients of cefotaxime sodium. eHealthMe is studying from 2,527 Claforan users. Check the latest studies of Claforan.

On Jul, 12, 2026

44 people who take Vancomycin hcl and Claforan together, and have interactions are studied.

Vancomycin hcl and Claforan drug interactions.

What are the common drug interactions of Vancomycin Hcl and Claforan, by gender? *:

female:

Eye irritation
Genital rash (rash on sex organ)
Oral mucosal eruption (a sudden appearing of rash on mucous membrane of mouth)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Drug exposure during pregnancy
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Generalised erythema (redness of the skin all over the body)
Histiocytosis haematophagic

male:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Loss of consciousness
Anal polyp (abnormal growth sticking out from the mucous membrane lining the anus or colon)
Bacteraemia (presence of bacteria in the blood)
Carbuncle (a carbuncle is an abscess larger than a boil)
Cellulitis (infection under the skin)
Conjunctivitis (pink eye)
Constipation
Dehydration (dryness resulting from the removal of water)
Dermatitis diaper (diaper rash is a common form of inflamed skin)

What are the common drug interactions of Vancomycin Hcl and Claforan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal pain
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Hypersensitivity
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Oedema mouth (swelling of mouth)
Rash morbilliform (a rash that looks like measles)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thrombocytopenia (decrease of platelets in blood)

10-19:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Histiocytosis haematophagic
Multi-organ failure (multisystem organ failure)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Septic shock (shock due to blood infection)

20-29:

Cytolytic hepatitis (dissolution or destruction of a liver cell)
Drug exposure during pregnancy

30-39:

Transplant rejection (a transplant material is not worked)
Weight increased
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal distension
Anxiety
Blood bilirubin increased
C-reactive protein increased
Dyspnoea (difficult or laboured respiration)
Epstein-barr virus infection
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

40-49:

Pyrexia (fever)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Respiratory disorder (respiratory disease)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Aortic valve replacement
Asthenia (weakness)
Blood creatinine increased
C-reactive protein increased
Decreased appetite
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

50-59:

Blood culture positive
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Eye irritation
Genital rash (rash on sex organ)
Oral mucosal eruption (a sudden appearing of rash on mucous membrane of mouth)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)

60+:

Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Biliary cyst
Blood creatinine increased
Haematuria (presence of blood in urine)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Pancreatitis acute (sudden inflammation of pancreas)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Rash generalised (rash on most of body parts)
Renal failure acute (rapid kidney dysfunction)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)

What are the existing conditions these people have? *

Pneumonia: 4 people, 9.09%
Sedation: 3 people, 6.82%
Pain: 3 people, 6.82%
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 3 people, 6.82%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Vancomycin hcl and Claforan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously