Vancomycin hydrochloride and Naproxen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hydrochloride (vancomycin hydrochloride) and Naproxen (naproxen). Common drug interactions include diarrhoea among females and renal failure acute among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hydrochloride and Naproxen. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hydrochloride?

Vancomycin hydrochloride has active ingredients of vancomycin hydrochloride. It is often used in mrsa infection. eHealthMe is studying from 8,399 Vancomycin hydrochloride users. Check the latest studies of Vancomycin hydrochloride.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,033 Naproxen users. Check the latest studies of Naproxen.

On Aug, 09, 2026

45 people who take Vancomycin hydrochloride and Naproxen together, and have interactions are studied.

Vancomycin hydrochloride and Naproxen drug interactions.

What are the common drug interactions of Vancomycin Hydrochloride and Naproxen, by gender? *:

female:

Diarrhoea
Dyschezia (difficulty in defecating)
Eye swelling
Generalised oedema (swelling all over the body)
Ill-defined disorder
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Injection site pain
Injection site swelling
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

male:

Renal failure acute (rapid kidney dysfunction)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Malaise (a feeling of general discomfort or uneasiness)
Rash
Acute respiratory failure
Anaemia (lack of blood)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Vancomycin Hydrochloride and Naproxen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Blood osmolarity increased
Blood potassium decreased
Blood pressure decreased
Blood urea decreased
Blood urea increased
Blood uric acid decreased
Blood uric acid increased

20-29:

Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
Thrombocytopenia (decrease of platelets in blood)
Venoocclusive liver disease (small veins in the liver are obstructed)

30-39:

Abdominal discomfort
Drug intolerance (drug sensitivity)
Vomiting

40-49:

Cellulitis (infection under the skin)
Dyschezia (difficulty in defecating)
Eye swelling
Generalised oedema (swelling all over the body)
Ill-defined disorder
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Injection site pain
Injection site swelling
Ocular hyperaemia (an abnormally large amount of blood in eye)
Rash

50-59:

Headache (pain in head)
Heart rate decreased
Hypotension (abnormally low blood pressure)
Incontinence (lack of moderation or self-control)
Injury
Irritable bowel syndrome
Lactose intolerance (inability to digest lactose)
Large intestinal ulcer
Lower respiratory tract infection
Malaise (a feeling of general discomfort or uneasiness)

60+:

Renal failure acute (rapid kidney dysfunction)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Renal failure (kidney dysfunction)
Confusional state
Dizziness
Hyperhidrosis (abnormally increased sweating)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Asthenia (weakness)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 15.56%
High Blood Pressure: 6 people, 13.33%
High Blood Cholesterol: 5 people, 11.11%
Infection: 4 people, 8.89%
Device Related Infection: 4 people, 8.89%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 8.89%
Nausea (feeling of having an urge to vomit): 4 people, 8.89%
Leukopenia (less number of white blood cells in blood): 3 people, 6.67%
Stress And Anxiety: 3 people, 6.67%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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