Vascepa and Genvoya drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vascepa (icosapent ethyl) and Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate). Common drug interactions include anhedonia among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Vascepa and Genvoya. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.

What is Genvoya?

Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 13,538 Genvoya users. Check the latest studies of Genvoya.

On Aug, 01, 2026

22 people who take Vascepa and Genvoya together, and have interactions are studied.

What are the common drug interactions of Vascepa and Genvoya, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Drug ineffective
Emotional distress
Multiple fractures
Osteoporosis (bones weak and more likely to break)
Pain
Cervical vertebral fracture
Chronic kidney disease
Depression

male:

Emotional distress
Pain
Gait disturbance
Bone loss
Osteonecrosis (death of bone)
Asthenia (weakness)
Blood creatinine increased
Creatinine urine increased
Decreased activity
Depression

What are the common drug interactions of Vascepa and Genvoya, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Femur fracture
Foot fracture
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Bone density decreased

40-49:

Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Gait disturbance
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

50-59:

Osteopenia (a condition where bone mineral density is lower than normal)
Asthenia (weakness)
Bone loss
Creatinine urine increased
Decreased activity
Dysuria (painful or difficult urination)
Gait disturbance
Lower limb fracture
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)

60+:

Depression
Headache (pain in head)
Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 27.27%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 18.18%
Diabetes: 4 people, 18.18%
Cardiac Disorder: 4 people, 18.18%
Urinary Retention (the inability to completely or partially empty the bladder): 2 people, 9.09%
Inflammation: 2 people, 9.09%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 2 people, 9.09%
Hypotension (abnormally low blood pressure): 2 people, 9.09%
Hypersensitivity: 2 people, 9.09%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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