Venclexta and Zanaflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Venclexta (venetoclax) and Zanaflex (tizanidine hydrochloride). Common drug interactions include pulmonary mass among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Venclexta and Zanaflex. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Venclexta?

Venclexta has active ingredients of venetoclax. eHealthMe is studying from 31,425 Venclexta users. Check the latest studies of Venclexta.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.



On Jun, 28, 2026

32 people who take Venclexta and Zanaflex together, and have interactions are studied.

Venclexta and Zanaflex drug interactions.

What are the common drug interactions of Venclexta and Zanaflex, by gender? *:

female:

  1. Pulmonary mass
  2. Headache (pain in head)
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Deafness
  5. Dizziness
  6. Escherichia infection (bacterial infection by escherichia coli)
  7. Fall
  8. Hypersensitivity
  9. Hypertension (high blood pressure)
  10. Hypotension (abnormally low blood pressure)

male:

  1. Pneumonia
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Chronic kidney disease
  4. Chronic respiratory failure
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
  9. Hypoxia (low oxygen in tissues)
  10. Leukaemia (blood or bone marrow cancer)

What are the common drug interactions of Venclexta and Zanaflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Pneumonia
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Staphylococcal infection (an infection with staphylococcus bacteria)
  4. Wound infection
  5. Memory impairment
  6. Hypotension (abnormally low blood pressure)
  7. Death
  8. Anaemia (lack of blood)
  9. Febrile neutropenia (fever with reduced white blood cells)
  10. Leukaemia (blood or bone marrow cancer)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 15 people, 46.88%
  2. Nausea (feeling of having an urge to vomit): 15 people, 46.88%
  3. Pain: 10 people, 31.25%
  4. Nausea And Vomiting: 9 people, 28.12%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 25.00%
  6. Dizziness: 8 people, 25.00%
  7. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 15.62%
  8. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 5 people, 15.62%
  9. Spinal Pain (pain in spine): 5 people, 15.62%
  10. Rashes (redness): 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Venclexta and Zanaflex?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Venclexta and Zanaflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zanaflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Venclexta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zanaflex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on venetoclax and tizanidine hydrochloride (the active ingredients of Venclexta and Zanaflex, respectively), and Venclexta and Zanaflex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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