Viberzi and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viberzi (eluxadoline) and Ibuprofen (ibuprofen). Common drug interactions include chronic kidney disease among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Viberzi and Ibuprofen. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Viberzi?

Viberzi has active ingredients of eluxadoline. eHealthMe is studying from 3,077 Viberzi users. Check the latest studies of Viberzi.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

On Jul, 11, 2026

30 people who take Viberzi and Ibuprofen together, and have interactions are studied.

Viberzi and Ibuprofen drug interactions.

What are the common drug interactions of Viberzi and Ibuprofen, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anxiety
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Fatigue (feeling of tiredness)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Oral fungal infection

male:

Anxiety
Hepatic steatosis (fatty liver disease)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Platelet count decreased
Renal failure (kidney dysfunction)
Urinary tract infection
Wrist fracture

What are the common drug interactions of Viberzi and Ibuprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Chest discomfort
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral coldness
Tendonitis (a condition that causes pain and swelling of tendons)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight decreased

40-49:

Anxiety
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Oral fungal infection
Oral mucosal erythema (redness of the mucous membrane of mouth)
Stomatitis (inflammation of mucous membrane of mouth)
Back injury

50-59:

Disease progression
Nausea (feeling of having an urge to vomit)

60+:

Fatigue (feeling of tiredness)
Chronic kidney disease
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic steatosis (fatty liver disease)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Platelet count decreased
Urinary tract infection
Wrist fracture

What are the existing conditions these people have? *

Irritable Bowel Syndrome: 7 people, 23.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 20.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 16.67%
Stress And Anxiety: 4 people, 13.33%
Asthma: 4 people, 13.33%
Diarrhea: 4 people, 13.33%
Abdominal Discomfort: 3 people, 10.00%
Insomnia (sleeplessness): 3 people, 10.00%
Depression: 3 people, 10.00%
Sleep Disorder: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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