Vibramycin and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vibramycin (doxycycline) and Compazine (prochlorperazine maleate). Common drug interactions include drug hypersensitivity among females and bacteraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Vibramycin and Compazine. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Vibramycin?

Vibramycin has active ingredients of doxycycline. It is often used in acne. eHealthMe is studying from 1,692 Vibramycin users. Check the latest studies of Vibramycin.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Aug, 07, 2026

14 people who take Vibramycin and Compazine together, and have interactions are studied.

Vibramycin and Compazine drug interactions.

What are the common drug interactions of Vibramycin and Compazine, by gender? *:

female:

Drug hypersensitivity
Anaemia (lack of blood)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Hyperglycaemia (high blood sugar)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Lymphocyte count decreased
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Urinary tract infection
Abdominal pain lower

male:

Bacteraemia (presence of bacteria in the blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Renal cancer (cancer of kidney)
Small intestinal obstruction (blockage in small intestine)
Disease progression
Drug eruption (adverse drug reaction of the skin)
Hypotension (abnormally low blood pressure)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Lung adenocarcinoma stage iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver)
Night sweats (sweating in night)

What are the common drug interactions of Vibramycin and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Atrial thrombosis (blood clot that develops in an artery)

30-39:

n/a

40-49:

Drug hypersensitivity
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

Anaemia (lack of blood)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Hyperglycaemia (high blood sugar)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Lymphocyte count decreased
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Urinary tract infection
Drug eruption (adverse drug reaction of the skin)

60+:

Drug hypersensitivity
Bacteraemia (presence of bacteria in the blood)
Renal cancer (cancer of kidney)
Small intestinal obstruction (blockage in small intestine)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Disease progression
Hypotension (abnormally low blood pressure)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Lung adenocarcinoma stage iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver)
Night sweats (sweating in night)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Pain: 3 people, 21.43%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 14.29%
Constipation: 2 people, 14.29%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 1 person, 7.14%
Folliculitis (infection of hair root): 1 person, 7.14%
Enlarged Prostate: 1 person, 7.14%
Electrolyte Imbalance: 1 person, 7.14%
Diarrhea: 1 person, 7.14%
Diabetes: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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