Vicodin es and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin es (acetaminophen; hydrocodone bitartrate) and Colace (docusate ). Common drug interactions include intervertebral disc protrusion among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin es and Colace. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin es?

Vicodin es has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,450 Vicodin es users. Check the latest studies of Vicodin es.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 15, 2026

61 people who take Vicodin es and Colace together, and have interactions are studied.

Vicodin es and Colace drug interactions.

What are the common drug interactions of Vicodin Es and Colace, by gender? *:

female:

Intervertebral disc protrusion (spinal disc protrusion)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
Lhermitte's sign (an electrical sensation that runs down the back and into the limbs)
Lung disorder (lung disease)
Lung neoplasm (tumour of lung)
Malignant neoplasm progression (cancer tumour came back)
Nephrosclerosis (hardening of the kidney due to renovascular disease)
Oral disorder (mouth disease)
Oral infection
Oral mucosal exfoliation (removal of mucous membrane of mouth)

male:

Fatigue (feeling of tiredness)
White blood cell count increased
Night sweats (sweating in night)
Oedema (fluid collection in tissue)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pyrexia (fever)
Rash
Rhinorrhoea (watery mucus discharge from the nose)
Spinal pain (pain in spine)

What are the common drug interactions of Vicodin Es and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
Chronic kidney disease
Hypoglycaemia (deficiency of glucose in the bloodstream)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Type 1 diabetes mellitus

40-49:

n/a

50-59:

Depression
Sinusitis (inflammation of sinus)
Fatigue (feeling of tiredness)
Gait disturbance
Bone disorder
Chest pain
Cough
Headache (pain in head)
Muscular weakness (muscle weakness)
Osteonecrosis (death of bone)

60+:

Asthenia (weakness)
Fatigue (feeling of tiredness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Night sweats (sweating in night)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pyrexia (fever)
Rash
Rhinorrhoea (watery mucus discharge from the nose)
Spinal pain (pain in spine)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 14.75%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 13.11%
Back Pain: 7 people, 11.48%
Metastases To Bone (cancer spreads to bone): 6 people, 9.84%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 9.84%
Nausea (feeling of having an urge to vomit): 5 people, 8.20%
Chest Pain: 5 people, 8.20%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.56%
Multiple Myeloma (cancer of the plasma cells): 4 people, 6.56%
Breast Cancer Metastatic: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

Do you take Vicodin es and Colace?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously