Vimpat and Meropenem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimpat (lacosamide) and Meropenem (meropenem). Common drug interactions include hypertransaminasaemia among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Vimpat and Meropenem. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Meropenem?

Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.

On Jul, 15, 2026

73 people who take Vimpat and Meropenem together, and have interactions are studied.

What are the common drug interactions of Vimpat and Meropenem, by gender? *:

female:

Hypertransaminasaemia
Alanine aminotransferase increased
Respiratory failure (inadequate gas exchange by the respiratory system)
Amylase increased
Depressed level of consciousness
Device occlusion
Hyperbilirubinaemia (excess of bilirubin in the blood)
Infection
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

male:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Anaemia (lack of blood)
Acute hepatic failure
International normalised ratio increased
Anaemia folate deficiency (lack of blood due to deficiency of folate)
Dizziness
Fungal sepsis (whole body infection by fungus)
Urinary tract infection
Hypoxia (low oxygen in tissues)
Fall

What are the common drug interactions of Vimpat and Meropenem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Decreased immune responsiveness
Dysphagia (a condition in which swallowing is difficult or painful)
Pneumonia
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Salmonellosis (an infection with salmonella bacteria)

10-19:

n/a

20-29:

Blood creatine phosphokinase increased

30-39:

Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Anaemia (lack of blood)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Device dislocation
Hepatic enzyme increased
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Iron deficiency

40-49:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Central nervous system abscess (collection of pus in brain)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Influenza like illness
Acute hepatic failure
International normalised ratio increased
Gastritis (inflammation of stomach)
Interstitial lung disease
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)

50-59:

Klebsiella infection
Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Pyrexia (fever)
Rash
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Skin lesion

60+:

Infection
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Urinary tract infection
Hypoxia (low oxygen in tissues)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Electrocardiogram pq interval prolonged
Fall
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Pneumatosis intestinalis (air or gas in an intestine)

What are the existing conditions these people have? *

Pneumonia: 26 people, 35.62%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 20 people, 27.40%
Pain: 20 people, 27.40%
Sepsis (a severe blood infection that can lead to organ failure and death): 19 people, 26.03%
Depression: 16 people, 21.92%
Insomnia (sleeplessness): 16 people, 21.92%
Stress And Anxiety: 15 people, 20.55%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 15 people, 20.55%
Arrhythmias (irregular heartbeat): 14 people, 19.18%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 14 people, 19.18%

* Approximation only. Some reports may have incomplete information.

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