Vimpat and Nuplazid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimpat (lacosamide) and Nuplazid (pimavanserin tartrate). Common drug interactions include hallucination, visual among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Vimpat and Nuplazid. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Nuplazid?

Nuplazid has active ingredients of pimavanserin tartrate. eHealthMe is studying from 47,103 Nuplazid users. Check the latest studies of Nuplazid.

On Jul, 15, 2026

55 people who take Vimpat and Nuplazid together, and have interactions are studied.

What are the common drug interactions of Vimpat and Nuplazid, by gender? *:

female:

Hallucination, visual (seeing things that aren't there)
Hallucination (an experience involving the perception of something not present)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug ineffective
Abnormal behaviour
Fall
Loss of consciousness
Presyncope
Stress
Therapeutic response decreased (less preventive response)

male:

Hallucination (an experience involving the perception of something not present)
Malaise (a feeling of general discomfort or uneasiness)
Eating disorder
Flat affect (absence of emotional response to a situation)
Personality change
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Sepsis (a severe blood infection that can lead to organ failure and death)
Therapeutic response unexpected
Weight decreased
Pain in extremity

What are the common drug interactions of Vimpat and Nuplazid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cystitis (inflammation of the wall of the bladder)
Exostosis (formation of new bone on the surface of a bone)
Fall
Pyrexia (fever)
Somnolence (a state of near-sleep, a strong desire for sleep)
Throat tightness
Anxiety
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nausea (feeling of having an urge to vomit)
Overdose

60+:

Hallucination (an experience involving the perception of something not present)
Hallucination, visual (seeing things that aren't there)
Stress
Therapeutic response decreased (less preventive response)
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Swelling face
Vision blurred
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Parkinson's Disease: 38 people, 69.09%
Hallucinations (sensations that appear real but are created by your mind): 25 people, 45.45%
Delusion (a false belief or opinion): 18 people, 32.73%
Psychotic Disorder: 6 people, 10.91%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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