Vistaril and Peridex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Peridex (chlorhexidine gluconate). Common drug interactions include periodontal disease among females and international normalised ratio increased among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Peridex. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

On Jul, 20, 2026

26 people who take Vistaril and Peridex together, and have interactions are studied.

What are the common drug interactions of Vistaril and Peridex, by gender? *:

female:

Periodontal disease (disease that attacks the gum and bone and around the teeth)
Physical disability
Sinusitis (inflammation of sinus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Discomfort
Emotional distress
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gingivitis (inflammation of gums)
Neuropathy peripheral (surface nerve damage)
Osteonecrosis of jaw (death of bone of jaw)

male:

International normalised ratio increased
Abdominal pain
Infection
Injury
Metastases to bone (cancer spreads to bone)
Osteonecrosis of jaw (death of bone of jaw)
Purulent discharge (discharge that contains pus)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Aspartate aminotransferase increased
Back pain

What are the common drug interactions of Vistaril and Peridex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Adenovirus infection
Cystitis haemorrhagic (blood in the urine and painful voiding)
Diarrhoea
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Renal impairment (severely reduced kidney function)

10-19:

Abdominal pain
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Blood bilirubin increased
International normalised ratio increased
Blood alkaline phosphatase increased
Aspartate aminotransferase increased
Fatigue (feeling of tiredness)
Gamma-glutamyltransferase increased
Hepatic steatosis (fatty liver disease)

20-29:

n/a

30-39:

n/a

40-49:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gingivitis (inflammation of gums)
Injury
Neuropathy peripheral (surface nerve damage)
Osteomyelitis (infection of bone)
Pain
Pain in jaw
Parotitis (inflammation of a parotid gland)
Periodontal disease (disease that attacks the gum and bone and around the teeth)
Peroneal nerve palsy

50-59:

n/a

60+:

Deformity (disfigurement)
Pain
Periodontal disease (disease that attacks the gum and bone and around the teeth)
Physical disability
Purulent discharge (discharge that contains pus)
Sinusitis (inflammation of sinus)
Spinal osteoarthritis (joint cartilage loss in spine)
Asthenia (weakness)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Cardiac failure congestive

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 34.62%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 19.23%
Breast Cancer Metastatic: 4 people, 15.38%
Pain: 3 people, 11.54%
Nausea (feeling of having an urge to vomit): 3 people, 11.54%
Headache (pain in head): 3 people, 11.54%
Flatulence (flatus expelled through the anus): 2 people, 7.69%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 7.69%
Blood Creatinine Increased: 2 people, 7.69%
Constipation: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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